Collateral Requirements and Corporate Policy Decisions

Biguri, Kizkitza; Stahl, Jörg R.

doi:10.2139/ssrn.3375634

Cited by 2 publications

(2 citation statements)

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“…The i2i application offers individual tools for data and feature input, image viewing, image normalization, image scaling, one-point quantification, and region-of-interest (ROI) analysis ( Figure 1 ). The operator can select to visualize ion images with different colormaps, 39 tune the image brightness based on intensity or relative abundance, and remove hot pixels (i.e., pixels with extreme outlying intensities) with the automatic contrast adjustment tool, which sets the color scale maximum to the user defined n th percentile of the intensities. Additionally, the i2i software enables customized features based on experimental parameters.…”

Section: Results and Discussionmentioning

confidence: 99%

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Ion-to-Image, i2i, a Mass Spectrometry Imaging Data Analysis Platform for Continuous Ionization Techniques

2023

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Mass spectrometry imaging (MSI) techniques generate data that reveal spatial distributions of molecules on a surface with high sensitivity and selectivity. However, processing large volumes of mass spectrometry data into useful ion images is not trivial. Furthermore, data from MSI techniques using continuous ionization sources where data are acquired in line scans require different data handling strategies compared to data collected from pulsed ionization sources where data are acquired in grids. In addition, for continuous ionization sources, the pixel dimensions are influenced by the mass spectrometer duty cycle, which, in turn, can be controlled by the automatic gain control (AGC) for each spectrum (pixel). Currently, there is a lack of data-handling software for MSI data generated with continuous ionization sources and AGC. Here, we present ion-to-image (i2i), which is a MATLAB-based application for MSI data acquired with continuous ionization sources, AGC, high resolution, and one or several scan filters. The source code and a compiled installer are available at . The application includes both quantitative, targeted, and nontargeted data processing strategies and enables complex data sets to be processed in minutes. The i2i application has high flexibility for generating, processing, and exporting MSI data both from simple full scans and more complex scan functions interlacing MSn and SIM scan data sets, and we anticipate that it will become a valuable addition to the existing MSI software toolbox.

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Section: Results and Discussionmentioning

confidence: 99%

“…The program was developed in MATLAB 2022a (MathWorks Inc., Natick, MA, U.S.A.) with the Bioinformatics Toolbox, Parallel Computing Toolbox, Image Processing Toolbox, and MATLAB App Designer. The colormap viridis and copyUIaxes functions were downloaded from MATLAB file exchange. , …”

Section: Methodsmentioning

confidence: 99%