With the advent of the MOOCs era, the college English teaching mode is undergoing revolutionary changes. The restrictions of traditional teaching methods gradually emerged, and the English education model based on MOOCs emerged. MOOCs not only expand the teaching space, but also provide rich multimedia resources and interactive opportunities, promoting learning from the traditional classroom to a new era of autonomy, interaction and personalization. College English teaching in the MOOCs era is not only the teaching of knowledge, but also an educational change synchronized with The Times, which opens up a new possibility for cultivating globally competitive language specialists. Based on this, this paper aims to deeply explore the MOOC-based college English teaching model, from curriculum design to practice cases, to explore its challenges and countermeasures, in order to provide useful inspiration for future educational practice.