ChatGPT technology came into being in the era of artificial intelligence, and its impact on the field of education has attracted wide attention from the academic community. Among them, the participation of ChatGPT will promote the transformation of the interaction between teachers and students, from the traditional dual structure to the teacher-student-machine ternary human-computer cooperation model. This paper aimed to explore the influence of ChatGPT technology on teacher-student interaction in university. Status, opportunities, and challenges of ChatGPT participation in teacher-student interaction are found to be the main part of the findings. Through interviews with university teachers and students who used ChatGPT to participate in interaction. It is found that ChatGPTs involvement in teacher-student interaction can provide a large number of high-quality information resources for teachers and students in real-time according to their individual needs. At the same time, it can also be used as a medium for teachers and students to better and equally communicate, bridge intergenerational differences, and help to achieve benign teacher-student interaction. On the other hand, the teacher-student interaction has become more complicated. Indirectly, the traditional authority of teachers has been threatened. In addition to the lack of supervision means of ChatGPT in the education field currently, some students rely on AI to replace themselves to complete academic tasks. Besides, academic misconduct also occurs frequently, which challenges teacher-student interaction. Given the above research results, relevant suggestions are put forward to meet the challenges.