Collision of basal cell carcinoma and atypical fibroxanthoma

Perandones‐González, Héctor; Narganes, Luis Miguel Valladares; Moran, Mark; Prieto, Manuel Ángel Rodríguez

doi:10.25259/ijdvl_220_2021

Cited by 2 publications

(1 citation statement)

References 15 publications

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“…2,3 The occurrence of both these neoplasms at 1 site was first reported by Alves et al 4 Since then, only 3 other cases have been reported. [5][6][7] Although AFX typically follows an indolent clinical course, rapid growth can lead to local destruction with significant morbidity, and rare instances of perineural invasion and metastasis have been documented within the literature. [8][9][10] We report a case of this unusual collision tumor (AFX and basal cell carcinoma) presenting as a lesion on the parietal scalp.…”

Section: Introductionmentioning

confidence: 99%

A Tale of Two Tumors: A Collision Tumor of Atypical Fibroxanthoma and Basal Cell Carcinoma

Dhaliwal,

Sayyadioskoie,

Siatecka

et al. 2024

The American Journal of Dermatopathology

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A collision tumor is an infrequent phenomenon characterized by the presence of 2 histologically distinct tumor types (either benign or malignant) occurring within the same specific anatomical site. We describe a rare case of co-occurrence of basal cell carcinoma and atypical fibroxanthoma presenting as a single lesion on the scalp in a 76-year-old man. The lesion was clinically suspicious for basal cell carcinoma and biopsied. Histologic examination showed 2 distinct tumors, one with basaloid cells and the other one with pleomorphic spindle cells colliding and growing together. Immunohistochemical stains were crucial in establishing the diagnosis. This presentation is exceedingly rare and requires additional evaluation for diagnosis.

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