Colloidal KLu3F10:Tb3+ persistent luminescence nanocrystal based flexible detectors for 3D X-ray imaging

Xie, Fei; Chen, Dongxun; Zhang, Yi; Lv, Xulong; Chen, Xin; Sun, Kangning; Liang, Yanjie

doi:10.1039/d3tc03409g

J. Mater. Chem. C

2023

DOI: 10.1039/d3tc03409g

|View full text |Cite

Colloidal KLu₃F₁₀:Tb³⁺ persistent luminescence nanocrystal based flexible detectors for 3D X-ray imaging

Fei Xie,

Dongxun Chen,

Yi Zhang

et al.

Abstract: Scintillator-based X-ray detection and imaging have demonstrated significant potential in the domains of industrial safety inspection and medical diagnosis. However, developing X-ray detectors capable of effectively imaging three-dimensional objects with...

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

2025

Publication Types

Select...

Article5

Relationship

Self Cite0

Independent5

Authors

Journals

Cited by 6 publications

References 55 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Heterovalent Co‐Doped LiLuF₄ Composite Flexible Films as Persistent Luminescence Scintillator for X‐Ray High‐Resolution Extension Imaging

Lu,

Xu,

et al. 2024

Advanced Optical Materials

View full text Add to dashboard Cite

Scintillators with high light yield, spatial resolution, and detection sensitivity are desirable for X‐ray imaging. Howerer, it remains challenging to improve the light yield and radiation detection capability of alkali metal rare‐earth fluoride (ALnF4). Herein, a type of Cu2+ ion heterovalent co‐doped LiLuF4:Tb,Cu microcrystalline scintillation material with high light yield, persistent, and thermostimulated luminescence is obtained by defect engineering. The heterovalent codoping strategy not only increases the radioluminescence (RL) intensity, but also introduces more carrier traps in the material to enhance the long‐afterglow and thermoluminescence intensity of LiLuF4:Tb microcrystals. After doping of 3 mol% Cu2+ ions, the RL efficiency is increased by 88.61%, and the X‐ray detection limit of LiLuF4:Tb,Cu reaches 2.7928 nGy·s‒1. This detectivity is considerably lower than the medical imaging requirements (5.5 µGy·s‒1). Furthermore, a large‐area flexible scintillation film of dimensions 30 × 30 cm2 is prepared to achieve high spatial resolution X‐ray imaging of 22 LP mm−1@MTF(modulation transfer function) = 0.2. Besides, this flexible film enables X‐ray imaging of curved objects and stores optical information for >48 h. This work provides a paradigm for improving the RL intensity and X‐ray detection sensitivity of alkali rare‐earth fluorides by crystal defect engineering, and enriches X‐ray high resolution extended imaging applications.

show abstract

Heterovalent Co‐Doped LiLuF₄ Composite Flexible Films as Persistent Luminescence Scintillator for X‐Ray High‐Resolution Extension Imaging

Lu,

Xu,

et al. 2024

Advanced Optical Materials

View full text Add to dashboard Cite

show abstract

Inorganic metal oxide material BaSiO3:Eu2+ for convenient 3D X-ray imaging

Shen,

Zhang,

Jin

et al. 2024

Journal of Luminescence

View full text Add to dashboard Cite

X-ray/γ-ray/Ultrasound-Activated Persistent Luminescence Phosphors for Deep Tissue Bioimaging and Therapy

Wei,

Wang

2024

ACS Appl. Mater. Interfaces

View full text Add to dashboard Cite

Persistent luminescence phosphors (PLPs) can remain luminescent after excitation ceases and have been widely explored in bioimaging and therapy since 2007. In bioimaging, PLPs can efficiently avoid tissue autofluorescence and light scattering interference by collecting persistent luminescence signals after the end of excitation. Outstanding signal-to-background ratios, high sensitivity, and resolution have been achieved in bioimaging with PLPs. In therapy, PLPs can continuously produce therapeutic molecules such as reactive oxygen species after removing excitation sources, which realizes sustained therapeutic activity after a single dose of light stimulation. However, most PLPs are activated by ultraviolet or visible light, which makes it difficult to reactivate the PLPs in vivo, particularly in deep tissues. In recent years, excitation sources with deep tissue penetration have been explored to activate PLPs, including X-ray, γ-ray, and ultrasound. Researchers found that various inorganic and organic PLPs can be activated by X-ray, γ-ray, and ultrasound, making these PLPs valuable in the imaging and therapy of deep-seated tumors. These X-ray/γ-ray/ultrasound-activated PLPs have not been systematically introduced in previous reviews. In this review, we summarize the recently developed inorganic and organic PLPs that can be activated by X-ray, γ-ray, and ultrasound to produce persistent luminescence. The biomedical applications of these PLPs in deep-tissue bioimaging and therapy are also discussed. This review can provide instructions for the design of PLPs with deep-tissue-renewable persistent luminescence and further promote the applications of PLPs in phototheranostics, noninvasive biosensing devices, and energy harvesting.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Colloidal KLu₃F₁₀:Tb³⁺ persistent luminescence nanocrystal based flexible detectors for 3D X-ray imaging

Abstract: Scintillator-based X-ray detection and imaging have demonstrated significant potential in the domains of industrial safety inspection and medical diagnosis. However, developing X-ray detectors capable of effectively imaging three-dimensional objects with...

Cited by 6 publications

References 55 publications

Heterovalent Co‐Doped LiLuF₄ Composite Flexible Films as Persistent Luminescence Scintillator for X‐Ray High‐Resolution Extension Imaging

Heterovalent Co‐Doped LiLuF₄ Composite Flexible Films as Persistent Luminescence Scintillator for X‐Ray High‐Resolution Extension Imaging

Inorganic metal oxide material BaSiO3:Eu2+ for convenient 3D X-ray imaging

X-ray/γ-ray/Ultrasound-Activated Persistent Luminescence Phosphors for Deep Tissue Bioimaging and Therapy

Contact Info

Product

Resources

About

Colloidal KLu3F10:Tb3+ persistent luminescence nanocrystal based flexible detectors for 3D X-ray imaging

Abstract: Scintillator-based X-ray detection and imaging have demonstrated significant potential in the domains of industrial safety inspection and medical diagnosis. However, developing X-ray detectors capable of effectively imaging three-dimensional objects with...

Cited by 6 publications

References 55 publications

Heterovalent Co‐Doped LiLuF4 Composite Flexible Films as Persistent Luminescence Scintillator for X‐Ray High‐Resolution Extension Imaging

Heterovalent Co‐Doped LiLuF4 Composite Flexible Films as Persistent Luminescence Scintillator for X‐Ray High‐Resolution Extension Imaging

Inorganic metal oxide material BaSiO3:Eu2+ for convenient 3D X-ray imaging

X-ray/γ-ray/Ultrasound-Activated Persistent Luminescence Phosphors for Deep Tissue Bioimaging and Therapy

Contact Info

Product

Resources

About

Colloidal KLu₃F₁₀:Tb³⁺ persistent luminescence nanocrystal based flexible detectors for 3D X-ray imaging

Heterovalent Co‐Doped LiLuF₄ Composite Flexible Films as Persistent Luminescence Scintillator for X‐Ray High‐Resolution Extension Imaging

Heterovalent Co‐Doped LiLuF₄ Composite Flexible Films as Persistent Luminescence Scintillator for X‐Ray High‐Resolution Extension Imaging