2020
DOI: 10.1016/j.chemphyslip.2020.104981
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Colloidal lipid nanodispersion enriched hydrogel of antifungal agent for management of fungal infections: Comparative in-vitro, ex-vivo and in-vivo evaluation for oral and topical application

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Cited by 25 publications
(6 citation statements)
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“…Average particle size as depicted by peak was recorded 45.13 nm, which is considered suitable for skin application. 33 Poly dispersity index (PDI) value was found to be .137 and narrow PDI value indicates less aptitude to form clusters.
Figure 2.Particle size measurement of nanogels.
…”
Section: Resultsmentioning
confidence: 99%
“…Average particle size as depicted by peak was recorded 45.13 nm, which is considered suitable for skin application. 33 Poly dispersity index (PDI) value was found to be .137 and narrow PDI value indicates less aptitude to form clusters.
Figure 2.Particle size measurement of nanogels.
…”
Section: Resultsmentioning
confidence: 99%
“…Findings showed drug release in a sustained manner besides improved permeability. Outcomes clearly stated that SLN and SLN-H formulations might also be viewed as effective vehicles for the delivery of KZ orally and topically to ameliorate control over systemic and topical fungal infections [ 152 ]. A luliconazole nanocrystal (LNC) integrated hydrogel formulation was prepared for fungal infections by Kumar et al Findings demonstrated that drug retention from LNC hydrogel (N-GEL) was highest and highly efficient in fungus eradication.…”
Section: Hydrogel Drug Delivery Systems In Various Disordersmentioning
confidence: 99%
“… 10 , 13 , 20–22 Lipid nanocarriers are easy to prepare, biocompatible, nonirritant, sustain drug release, and have been reported to improve ocular penetration of many active pharmaceutical ingredients. 23 , 24 NLCs have been developed as second-generation lipid-based nanoparticles to overcome the drawbacks of low entrapment efficiency (EE) and drug expulsion on storage associated with solid lipid nanoparticles (SLNs). 25 , 26 A less ordered solid lipid matrix structure that is created by the addition of a liquid lipid to the solid lipid, to convert SLNs to NLCs, is the main factor behind increasing drug load within the formulation and improving stability during storage.…”
Section: Introductionmentioning
confidence: 99%