Colloidal Microrobotic Swarms

Zou, Qian; Wang, Yibin; Yu, Jiangfan

doi:10.1007/978-3-030-80197-7_8

Cited by 3 publications

(2 citation statements)

References 47 publications

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“…endoscopes and capsules 1 , 2 ), micrometers (e.g. microrobots 3 – 6 ) to nanometers (nanoparticles). The latter are employed in drug delivery (magnetic drug delivery or targeting 7 – 9 ), tissue manipulation (by actuation 10 , hyperthermia 11 , 12 , or other localized therapies 13 , 14 ) at target sites.…”

Section: Introductionmentioning

confidence: 99%

A comprehensive approach to characterize navigation instruments for magnetic guidance in biological systems

Blümler,

Raudzus,

Schmid

2024

Sci Rep

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Achieving non-invasive spatiotemporal control over cellular functions, tissue organization, and behavior is a desirable aim for advanced therapies. Magnetic fields, due to their negligible interaction with biological matter, are promising for in vitro and in vivo applications, even in deep tissues. Particularly, the remote manipulation of paramagnetic (including superparamagnetic and ferromagnetic, all with a positive magnetic susceptibility) entities through magnetic instruments has emerged as a promising approach across various biological contexts. However, variations in the properties and descriptions of these instruments have led to a lack of reproducibility and comparability among studies. This article addresses the need for standardizing the characterization of magnetic instruments, with a specific focus on their ability to control the movement of paramagnetic objects within organisms. While it is well known that the force exerted on magnetic particles depends on the spatial variation (gradient) of the magnetic field, the magnitude of the field is often overlooked in the literature. Therefore, we comprehensively analyze and discuss both actors and propose a novel descriptor, termed ‘effective gradient’, which combines both dependencies. To illustrate the importance of both factors, we characterize different magnet systems and relate them to experiments involving superparamagnetic nanoparticles. This standardization effort aims to enhance the reproducibility and comparability of studies utilizing magnetic instruments for biological applications.

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Section: Introductionmentioning

confidence: 99%

A comprehensive approach to characterize navigation instruments for magnetic guidance in biological systems

Blümler,

Raudzus,

Schmid

2024

Sci Rep

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“…To date, different types of external fields have been applied to actuate micro/nanoagents (Figure ), including magnetic, − electric, − optical, − and acoustic fields. − In addition to these fields, chemical reaction − and topographical patterns − have also been investigated to power and guide the agents, respectively. Existing reviews have focused on individual micro/nanoagents, including their evolution, fabrication and functionalization, − modeling and motion control, − biomedical applications, − and environmental applications. − Compared with a single agent, micro/nanorobotic swarms have higher robustness (e.g., higher tolerance to the failure of a few agents), higher motion dexterity and flexibility, and better scalability. They are poised to transform biology and medicine because of their large surface-to-volume ratio for drug loading, capability of maintaining integrity in resistance to external disturbances, and compatibility with many imaging modalities.…”

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confidence: 99%

Micro/Nanorobotic Swarms: From Fundamentals to Functionalities

Law

Tang

et al. 2023

ACS Nano

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Swarms, which stem from collective behaviors among individual elements, are commonly seen in nature. Since two decades ago, scientists have been attempting to understand the principles of natural swarms and leverage them for creating artificial swarms. To date, the underlying physics; techniques for actuation, navigation, and control; fieldgeneration systems; and a research community are now in place. This Review reviews the fundamental principles and applications of micro/ nanorobotic swarms. The generation mechanisms of the emergent collective behaviors among the micro/nanoagents identified over the past two decades are elucidated. The advantages and drawbacks of different techniques, existing control systems, major challenges, and potential prospects of micro/nanorobotic swarms are discussed.

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Dynamic Path Planning and Motion Control of Microrobotic Swarms for Mobile Target Tracking

Zou

Liu

et al. 2023

IEEE Trans. Automat. Sci. Eng.

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Colloidal Microrobotic Swarms

Cited by 3 publications

References 47 publications

A comprehensive approach to characterize navigation instruments for magnetic guidance in biological systems

A comprehensive approach to characterize navigation instruments for magnetic guidance in biological systems

Micro/Nanorobotic Swarms: From Fundamentals to Functionalities

Dynamic Path Planning and Motion Control of Microrobotic Swarms for Mobile Target Tracking

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