“…Although used in only five patients, endoscopic ultrasonography (EUS) is reported to play a key role in the preoperative assessment by virtue of its accurancy in defining invasion depth and nodal involvement, thereby helping surgeons to choose the most appropriate surgical approach and entity of resection. 7,[42][43][44] Differently from colonic LMSs, where preoperative biopsy and accurate radiological diagnosis/staging are sometimes not reported due to the emergency setting of surgery (obstruction, bleeding, or perforation), [45][46][47] rLMSs are all reported in elective setting, and therefore any effort should be made for the best preoperative work up. rLMSs patients should be meticulously studied and all available diagnostic tools and techniques, starting from a systematic digital exploration to imaging and EUSs, are needed, especially in the case of an inconclusive preoperative histology.…”