COLOFIT: Development and internal-external validation of models using age, sex, faecal immunochemical and blood tests to optimise diagnosis of colorectal cancer in symptomatic patients
CJ Crooks,
J West,
J Jones
et al.
Abstract:ObjectiveTo develop and validate a model using available information at the time of Faecal Immunochemical testing (FIT) in primary care to improve selection of symptomatic patients for colorectal cancer (CRC) investigations.DesignPopulation based cohort study.SettingAll adults ≥ 18 years of age referred to Nottingham University Hospitals NHS Trust between 2018 and 2022 with symptoms of suspected CRC who had a FIT.ParticipantsThe derivation cohort (Nov/2017- Nov/2021) included 34,435 patients with FIT results w… Show more
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