Colombian consensus on the diagnosis, treatment, and prevention of Candida Spp. disease in children and adults*,+

Oñate, José Manuel Castellanos; Rivas, Pilar Cebollero; Pallares, Christian; Trujillo, Carlos Humberto Saavedra; Martínez, Ernesto; Coronell, Wilfrido; López, Eduardo; Berrío, Indira; Álvarez-Moreno, Carlos; Roncancio, Gustavo; J, Segura; Vélez, Juan D.; Cortés, Jorge Alberto; Parra-Giraldo, Claudia Marcela; Álvarez, Jorge; Romero, Andrés F.; Zuluaga, Iván; Camacho, Germán

doi:10.22354/in.v23i3.792

Cited by 11 publications

(13 citation statements)

References 93 publications

(197 reference statements)

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“…Montravers et al 27 were able to demonstrate that in a nosocomial environment Candida spp. only was an independent risk factor for death, in contrast to patients with peritonitis from the community 27,68 . Empirical antifungal therapy can be included in the following cases: immunocompromised patients due to cancer, autoimmune disease or recent stem cell transplantation, or patients in the intensive care unit.…”

Section: Recommendation Number 32: What Is the Recommendation For The Initiation Of Antifungal Therapy According To The Population At Rismentioning

confidence: 84%

“…can improve the outcome. The underlying cause and the host's poor immune response to inflammatory stress are perhaps the biggest contributor to infection and outcome 68 .…”

Section: Recommendation Number 32: What Is the Recommendation For The Initiation Of Antifungal Therapy According To The Population At Rismentioning

confidence: 99%

“…No prospective study has formally validated the rationale for antifungal therapy. However, in view of the clinical severity, it seems reasonable to initiate empirical antifungal therapy in this setting 68 .…”

Section: Recommendation Number 32: What Is the Recommendation For The Initiation Of Antifungal Therapy According To The Population At Rismentioning

confidence: 99%

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Consensus Recommendations Based on Evidence for Abdominal Sepsis in the Pediatric and Adult Population of Colombia

Oñate

Gutiérrez

Esparza

et al. 2021

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Intra-abdominal infections are frequent at all levels of health care, therefore, it is necessary to maintain a high level of clinical suspicion, performing the fastest and most cost-effective measures to confirm the diagnosis and offer a precise and targeted multidisciplinary therapy, this being the only way to have an impact on the morbidity of this infection, reducing mortality and minimizing the complications and costs of health care. Intra-abdominal infections are linked to the appearance and selection of resistant mutants in both bacteria and fungi, becoming currently a major public health problem. Increasing bacterial resistance when associated with a greater possibility of difficulties in antimicrobial treatment increases mortality. This evidence-based consensus brings together the recommendations for the diagnosis and treatment of intra-abdominal infections in the pediatric and adult population. With strict monitoring of bacterial resistance and stimulating the control of the risk factors that have the greatest impact on the appearance of this phenomenon, this consensus is intended to be a practical guide that is easy to implement, and with periodic updates it will favor and facilitate multidisciplinary and the adequacy of the therapeutic management of intra-abdominal infections.

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Section: Recommendation Number 32: What Is the Recommendation For The Initiation Of Antifungal Therapy According To The Population At Rismentioning

confidence: 84%

“…can improve the outcome. The underlying cause and the host's poor immune response to inflammatory stress are perhaps the biggest contributor to infection and outcome 68 .…”

Section: Recommendation Number 32: What Is the Recommendation For The Initiation Of Antifungal Therapy According To The Population At Rismentioning

confidence: 99%

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Consensus Recommendations Based on Evidence for Abdominal Sepsis in the Pediatric and Adult Population of Colombia

Oñate

Gutiérrez

Esparza

et al. 2021

Infect

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“…El actual consenso colombiano de práctica clínica para el manejo de la candidemia es una adaptación de las guías internacionales, especialmente, la estadounidense y la europea 39 . También, se cuenta con el protocolo de estudio y manejo de pacientes con candidiasis sistémica de la Asociación Colombiana de Infectología (ACIN) 24 , el cual se resume en el cuadro 5 .…”

Section: Pronósticounclassified

Candidemia en Colombia

et al. 2020

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En Colombia, especialmente en las unidades de cuidados intensivos, la candidemia es una causa frecuente de infección del torrente sanguíneo y representa el 88 % de lasinfecciones fúngicas en pacientes hospitalizados, con una mortalidad entre 36 y 78 %. Su incidencia en Colombia es mayor a la reportada en los países desarrollados e, incluso, en otros países de Latinoamérica. Para su manejo deben considerarse los factores de riesgo del paciente, luego valorar las características clínicas y, finalmente, hacer los estudios microbiológicos y, si es necesario, pruebas moleculares.En general, las guías estadounidenses, latinoamericanas y europeas recomiendan las equinocandinas como el tratamiento de primera línea de la candidemia y difieren en el uso de fluconazol dependiendo de la ‘evidencia’, la gravedad de la enfermedad, la exposición previa a los azoles y la prevalencia de Candida no albicans. Dada su gran incidencia en nuestro país, asociada con una elevada mortalidad, esta infección debe buscarse sistemáticamente en pacientes con factores de riesgo, con el fin de iniciar oportunamente el tratamiento antifúngico.

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“…In this issue, Oñate J, et al 5 . describe the main recommendations for the diagnosis, treatment and prevention of infections caused by Candida spp.…”

mentioning

confidence: 98%

Antifungal stewardship: consensus on the diagnosis, treatment, and prevention of Candida spp. disease is a fundamental step in the road map to achieve it

Álvarez-Moreno

2019

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Colombian consensus on the diagnosis, treatment, and prevention of Candida Spp. disease in children and adults*,+

Cited by 11 publications

References 93 publications

Consensus Recommendations Based on Evidence for Abdominal Sepsis in the Pediatric and Adult Population of Colombia

Consensus Recommendations Based on Evidence for Abdominal Sepsis in the Pediatric and Adult Population of Colombia

Candidemia en Colombia

Antifungal stewardship: consensus on the diagnosis, treatment, and prevention of Candida spp. disease is a fundamental step in the road map to achieve it

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