Colon cancer metastasis to the sternum: palliative treatment with radiofrequency ablation and cement injection

Abstract

Colon cancer metastasis to bone is extremely rare and has devastating consequences on patients’ quality of life. Furthermore, radiofrequency ablation in conjunction with cementoplasty to nonweight bearing, flat bones has not been widely reported as palliative treatment for pain as a result of bone metastasis. Here, we present a case of a 47-year-old man who developed a sternal metastasis from an invasive adenocarcinoma of the colon originally diagnosed several years prior. The pain from the metastasis was originally treated with external beam radiation therapy, but after 6 weeks of continuous pain, it was retreated using radiofrequency ablation in conjunction with cementoplasty.

Selective in vitro cytotoxicity effect of Drimia calcarata bulb extracts against p53 mutant HT-29 and p53 wild-type Caco-2 colorectal cancer cells through STAT5B regulation

“…Thus, colorectal malignant growth can be effectively treated when identified early; however, at a later stage when the ailment has spread to different tissues, it becomes an arduous task to treat this disease [ 12 ]. Late diagnosis can result in a poor prognosis, but advanced colorectal cancer can be controlled by chemotherapy and radiotherapy [ 13 ]. For metastatic colorectal cancer patients, around 75 % continue to live beyond 1 year, 35 % beyond 3 years, and less than 20 % beyond 5 years after diagnosis.…”

Pain in mesothelioma: feasibility study of percutaneous image-guided radiofrequency ablation of chest wall lesions

“…Le complicanze hanno incluso: ustione cutanea, incontinenza fecale e urinaria transitorie dopo trattamento nella zona sacrale, e fratture dell'acetabolo. In molti casi l'RFA è utilizzata in combinazione con iniezione di "cemento" biocompatibile (vertebroplastica) come trattamento palliativo(Wessel et al, 2016).…”