Colon cancer presenting as amyotrophic dermatomyositis

Lee, Shing Fung; Lam, Y.C.J.; Mak, Siu Ming

doi:10.1136/postgradmedj-2018-135856

Cited by 1 publication

(1 citation statement)

References 4 publications

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“…In recent years, some cases of CADM patients with tumors have been reported successively [19,20], while CADM, compared with DM, seemed to be more susceptible to malignancy [21]. But it also has some difference with DM.…”

Section: Tumor Occurrencementioning

confidence: 99%

Rapidly Progressive Interstitial Lung Disease Originating from Clinically Amyopathic Dermatomyositis Associated with Positive Anti-MDA 5 Antibody: a Case Report and Literature Review

Huang

Mao

2019

SN Compr. Clin. Med.

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Clinically amyopathic dermatomyositis (CADM) is a rare auto-immune disease, which discriminates from classical dermatomyositis; it lacks typical muscle weakness, but has a high risk of developing rapid progressive interstitial lung disease (RP-ILD), malignancies, and other fatal complications, so it is easy to cause misdiagnosis and high mortality. To attract more attention and arouse more understanding, we cover and summarize our clinical findings. Here, we reported a male patient, who rapidly progressed to serious respiratory failure despite an aggressive treatment, a combination of methylprednisolone, cyclosporine, acetylcysteine, and intravenous immunoglobulin. He suffered from CADM with positive anti-melanoma differentiation-associated gene-5 (MDA 5) antibody. CADM, as a special phenotype of DM/PM (dermatomyositis/polymyositis), is usually rapidly progressive and fatal, which requires further investigation into specific pathogenesis and more effective diagnosis as well as treatment measures. Due to the severity and rarity, we simultaneously performed a review of recent literature to provide more theoretical references for clinicians in diagnosis and treatment and finally improve the survival rate of these patients.

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Section: Tumor Occurrencementioning

confidence: 99%