Colon capsule endoscopy

Fernández-Urién, Ignacio; Carretero, Cristina; Borda, Ana; Muñoz-Navas, Miguel

doi:10.3748/wjg.14.5265

Cited by 22 publications

(18 citation statements)

References 11 publications

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“…During this period, the capsule is likely to transit most of the small bowel and reaches approximately the level of terminal ileum. Recording and downloading of data are similar to those for small-bowel capsule endoscopy (7).…”

Section: Introductionmentioning

confidence: 99%

PillCam© Colon Capsule for the study of colonic pathology in clinical practice: Study of agreement with colonoscopy

Herrerías‐Gutiérrez

Argüelles-Arias

Caunedo-Álvarez

et al. 2011

Rev. esp. enferm. dig.

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Introduction: several studies have pointed out the effectiveness of the PillCam© colon capsule endoscopy (CCE) compared with the colonoscopy in the study of the colonic pathology.Aims and methods: the objective of our study was to assess the agreement in the diagnosis of CCE with conventional colonoscopy as well as its sensitivity and specificity, and to describe the findings of the CCE in our clinical practice. Consecutive patients with abdominal symptoms were included in the study. The CCE was performed as previously reported (with PEG and sodium phosphate as laxative agents). The nature and location of the findings, colonic transit time, complications, cleanliness degree and consistency with diagnostic colonoscopy, when performed, were analyzed.Results: a total of 144 subjects (67 women and 77 men); (52.17±16.71 years) with the following indications were included: screening of Colorectal cancer (88 patients), control after polipectomy (24), incomplete colonoscopy (7), rectal bleeding (10), anemia (8), diarrhea (7). The CCE exploration was complete in 134/144 cases (93%), with no case of retention. The preparation was good-very good in 88/134 (65,6%), fair in 26/134 (19,4%) and poor in 20/134 (15%) of the cases. The average colonic transit was of 140.76 min (9-603). Any adverse effect was notified.In 44 cases a colonoscopy was carried out after CCE (results were hidden from another endoscopist). Compared to colonoscopy, the rate of agreement was 75,6%, the sensitivity was 84% and the specificity 62,5%, PPV was 77,7% and NPV was 71,4 %.The colonic findings in 134 CCE were: in 34 cases CCE it did not show lesions, diverticulosis in 63 explorations, polyps in 43, angiodysplasias in 15, Crohn´s Disease in 9 and ulcerative colitis in other 8 cases.Conclusions: the CCE is an effective and reliable technique for the detection of lesions in colon, and because of its high agreement with the colonoscopy, it could be useful in clinical practice. Further studies with large seria and cost-effectiveness analysis are needed to confirm these data. INTRODUCTIONCapsule endoscopy has been established as the diagnosis of obscure gastrointestinal bleeding and in other small bowel suspected lesions (1-3) and it is known to be useful only for the study of small bowel mucosa injuried (4). Following the path marked by this capsule, a colon capsule endoscopy has been developed. Several studies have pointed out the effectiveness of the PillCam© colon capsule endoscopy (CCE) compared to the colonoscopy in the study of the colonic pathology (5,6).The CCE is similar to the conventional capsule but has two cameras which are able to record video images from both ends. The device measures 31 by 11 mms and acquires images at a rate of 4 frames per second. The preprogrammed "sleep" mode allows recording of images from the esophagus and the stomach for 3 minutes and after that capsule switches to sleep mode for 1 hour 45 minutes, so that it saves battery. During this period, the capsule is likely to transit most of the small bowel and reaches ap...

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Section: Introductionmentioning

confidence: 99%

PillCam© Colon Capsule for the study of colonic pathology in clinical practice: Study of agreement with colonoscopy

Herrerías‐Gutiérrez

Argüelles-Arias

Caunedo-Álvarez

et al. 2011

Rev. esp. enferm. dig.

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“…Colonoscopy is considered to be the most effective method for CRC screening due to the possibility of visualizing the inner surface of the colon, acquiring biopsies, and treating lesions as soon as they are detected [4,5]. However, take-up of screening colonoscopy is limited due to various factors including invasiveness, patient discomfort, fear of pain, and the need for sedation [6,7]. The technology behind flexible endoscopy basically consists of a long (approximately from 130 up to 160 cm), semirigid tube with a steerable head (diameter from 12 up to 14 mm).…”

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confidence: 99%

Magnetic air capsule robotic system: proof of concept of a novel approach for painless colonoscopy

et al. 2011

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Background Despite being considered the most effective method for colorectal cancer diagnosis, colonoscopy take-up as a mass-screening procedure is limited mainly due to invasiveness, patient discomfort, fear of pain, and the need for sedation. In an effort to mitigate some of the disadvantages associated with colonoscopy, this work provides a preliminary assessment of a novel endoscopic device consisting in a softly tethered capsule for painless colonoscopy under robotic magnetic steering. Methods The proposed platform consists of the endoscopic device, a robotic unit, and a control box. In contrast to the traditional insertion method (i.e., pushing from behind), a "front-wheel" propulsion approach is proposed. A compliant tether connecting the device to an external box is used to provide insufflation, passing a flexible operative tool, enabling lens cleaning, and operating the vision module. To assess the diagnostic and treatment ability of the platform, 12 users were asked to find and remove artificially implanted beads as polyp surrogates in an ex vivo model. In vivo testing consisted of a qualitative study of the platform in pigs, focusing on active locomotion, diagnostic and therapeutic capabilities, safety, and usability. Results The mean percentage of beads identified by each user during ex vivo trials was 85 ± 11%. All the identified beads were removed successfully using the polypectomy loop. The mean completion time for accomplishing the entire procedure was 678 ± 179 s. No immediate mucosal damage, acute complications such as perforation, or delayed adverse consequences were observed following application of the proposed method in vivo. Conclusions Use of the proposed platform in ex vivo and preliminary animal studies indicates that it is safe and operates effectively in a manner similar to a standard colonoscope. These studies served to demonstrate the platform's added advantages of reduced size, front-wheel drive strategy, and robotic control over locomotion and orientation.

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“…In fact, more than 1,000,000 procedures have been performed worldwide. Recently, new prototypes of capsule endoscopy, such as the PillCam™ ESO and the PillCam™ COLON, have been developed (5,6). Therefore, the examination areas are currently not limited only to the small bowel.…”

Section: Discussionmentioning

confidence: 99%

Avoiding incomplete conventional colonoscopies: PillCam™ COLON capsule endoscopy

Fernández-Urién

Ostiz

Jiménez

2011

Rev. esp. enferm. dig.

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Colon capsule endoscopy

Cited by 22 publications

References 11 publications

PillCam© Colon Capsule for the study of colonic pathology in clinical practice: Study of agreement with colonoscopy

PillCam© Colon Capsule for the study of colonic pathology in clinical practice: Study of agreement with colonoscopy

Magnetic air capsule robotic system: proof of concept of a novel approach for painless colonoscopy

Avoiding incomplete conventional colonoscopies: PillCam™ COLON capsule endoscopy

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Colon capsule endoscopy

Cited by 22 publications

References 11 publications

PillCam© Colon Capsule for the study of colonic pathology in clinical practice: Study of agreement with colonoscopy

PillCam© Colon Capsule for the study of colonic pathology in clinical practice: Study of agreement with colonoscopy

Magnetic air capsule robotic system: proof of concept of a novel approach for painless colonoscopy

Avoiding incomplete conventional colonoscopies: PillCam&trade; COLON capsule endoscopy

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Avoiding incomplete conventional colonoscopies: PillCam™ COLON capsule endoscopy