Colon carcinoma staging by endoscopic ultrasonography miniprobes

Abstract

Background and Objectives:Due to the increasing use of endoscopic techniques for colon cancer resection, pretreatment locoregional staging may gain critical interest. The use of endoscopic ultrasonography (EUS) miniprobes in this context has been seldom reported. Our aim was to determine the accuracy of EUS miniprobes for colon cancer staging.Materials and Methods:Forty patients with colon cancer (2 in the cecum, 9 in the ascending colon, 5 in the transverse colon, 5 in the descending colon, and 19 in the sigmoid colon) were submitted to staging using 12 MHz EUS miniprobes. EUS and the anatomopathological results were compared with regard to the T and N stages. It was assessed if the location, longitudinal extension, or circumferential extension of the tumor had any influence on the accuracy in EUS staging.Results:Tumor staging was feasible in 39 (98%) patients except in one case with a stenosing tumor (out of 6). Globally, T stage was accurately determined in 88% of the cases. In the assessment of the presence or absence of lymph node metastasis, miniprobes presented an accuracy of 82% with a sensitivity of 67%. These results were neither affected by the location nor by the longitudinal or circumferential extension of the tumor.Conclusions:EUS miniprobes may play an important role in assessing T and N stages in colon cancer and may represent an incentive to the research of new therapeutic areas for this disease.

A novel potential inflammation-nutrition biomarker for predicting lymph node metastasis in clinically node-negative colon cancer

“…Third, the indicators of grade and the T stage were obtained from the postoperative pathological analysis. Although the T stage and grade can be obtained preoperatively through imaging techniques and puncture, respectively, there is a possibility that the preoperative diagnosis may differ from the postoperative pathological findings ( 44 , 45 ). Fourth, further follow-up of patients is warranted to investigate the relationship between PALR and overall survival.…”

Az alsó tápcsatornai endoszkópos ultrahangvizsgálat

“…Bár az utóbbi években az endoszkópos ultrahang-miniszondák és az előretekintő echoendoszkópok kifejlesztése lehetőséget teremtett a végbélhez képest proximáli-sabban elhelyezkedő vastagbélrák stádiummeghatározására is, e módszerek alkalmazása a mindennapi gyakorlatban még nem terjedt el. A miniszondákat értékelő tanulmányok többsége nem vizsgálta külön azok pontosságát a végbél és az attól proximális vastagbél esetében, egy tanulmány ugyanakkor arról számol be, hogy a vastagbélrák ultrahangvizsgálattal történő stádiumbeosztása miniszondákkal 98%-ban volt kivitelezhető, a T-stádium-beosztás az esetek 88%-ában, az N-stádiummeghatározás pedig az esetek 82%-ában pontos [25,26].…”

Colorectal Endoscopic Submucosal Dissection: An Update on Best Practice

“…30 Although the utility of 12 MHz EUS mini-probes are not globally nor widely available, accuracy of diagnoses of T and N stages were 88% and 82%, respectively, regardless of the location or extension of the tumor. 31…”