Mucormycosis (zygomycosis) is an invasive fungal disease caused by
Rhizopus
species, most commonly implicated in diabetic ketoacidosis and other immunocompromised states. This report presents a unique case of colonic mucormycosis in a patient several weeks after liver transplant. The patient's course was complicated by polymicrobial infection and intra-abdominal abscesses, ultimately leading to septic shock and death. This case is the first of its kind to describe such malignant abdominal mucormycosis in a solid organ transplant recipient.