Colonic mucosubmucosal elongated polyp: report of a series of 14 cases and review of the literature

Abstract

CMSEPs show subtle but distinctive pathological features, and occur in normal and diseased colons. Pathologists need to be aware of this entity, to avoid confusion with other more commonly encountered colorectal polyps. With increasing colon cancer screening programmes and surveillance colonoscopy, it is likely that CMSEPs will be encountered more often.

Filiform polyposis presenting with rapid growth and severe anemia case report

“…According to the data in the literature, the average duration reported for formation since diagnosis with UC is approximately 3 to 276 months [5] . With a length up to 16 cm [9] , the sigmoid colon is the most common site [7] , [10] , which is consistent with the fact that 30–50 % of UCs are confined to the rectum and sigmoid colon [11] . The histopathological appearance of FP is generally normal to acute or chronic inflammatory colonic mucosa [10] , [12] .…”

Colonic Mucosubmucosal Elongated Polyp in the Sigmoid Colon on Surveillance Colonoscopy

“…The polyps have a clustered, slender appearance and are usually covered by inflamed colonic mucosa with occasional hyperplastic lymphoid follicles. 4,8…”

“…It has been identified in patients with inflammatory bowel disease, diverticular disease, colorectal adenoma or adenocarcinoma, and various other gastrointestinal or extra-gastrointestinal comorbidities, and in healthy subjects. 4,12 CMSEP is a benign lesion rarely causing clinical complications, but it has been reported in association with bleeding, intussusception, and, very rarely, cancerous transformation. Tozawa et al described continuous bleeding on the head of a CMSEP causing hematochezia and anemia in a patient with hemophilia inhibitor A.…”

“…4,5 The prevalence of CMSEP was estimated at 0.39%, representing 0.1% of all colorectal polyps. 1,3,4 CMSEP is most commonly located in the large bowel, especially sigmoid and transverse colon, but has also been reported in the small bowel with similar endoscopic features. 3,5,6…”

A Case of Inflammatory Fibroid Polyp with an Elongated Shape in Cecum

“…In addition, CMSEP has no inflammation such as lymphocytes, plasma cells, or eosinophils. [ 2 ] Other mesenchymal tumors, such as inflammatory myofibroblastic tumor, gastrointestinal stromal tumor, leiomyoma, and neurofibroma, should be distinguished through their typical morphology and immunophenotype.…”