Colonoscopic screening and follow-up for colorectal cancer in the elderly

Abstract

AIM: To improve the prevention and treatment of senile patients with colorectal cancer by evaluating the importance of colonoscopy in clinical screening and follow-up.METHODS: Clinical screening of colonoscopy was performed for 2196 patients aged 60-90 years old according to the protocol,and 1740 of them (79.2%) were followed-up. RESULTS:Colorectal cancer was found in 52 patients, and the detectable rate was 2.4%. Among them, 19 were diagnosed as early colorectal cancer, accounting for 36.5% of the detected colorectal cancer. Among the followed-up patients, early colorectal cancer was found in 9, accounting for 45.0% of the detected colorectal cancer. The resectable rate and 5 years survival rate of colorectal cancer were 97.7% and 80.9% respectively. The incidence of complication was 0.05%, and the successful rate of cecum intubation was 98.9%. CONCLUSION:Colonoscopic screening and follow-up of the elderly for colorectal cancer and pre-cancerous lesion (adenomatoid polyp) can increase the detectable rate of early colorectal cancer and improve its prevention and treatment.

Cancer Care Ontario Colonoscopy Standards: Standards and Evidentiary Base

“…Eight studies were obtained that reported on adenoma detection rates (11,15,32,35,39,40,60,62). The characteristics of the study populations varied across the reports.…”

“…No studies were obtained that provided data on patient assessment, infection control, monitoring during and after administration of conscious sedation, or resuscitation capability. However, the following data were provided in specific papers: perforation rate -eight papers (12,(17)(18)(19)(20)(21)60,61), bleeding -nine papers (12,13,18,(22)(23)(24)(25)60,61), cecal intubation rates -14 papers (11)(12)(13)(14)(15)17,18,(26)(27)(28)(29)(30)(31)60), average colonoscope withdrawal times -five papers (18,30,(32)(33)(34), adenoma detection -eight papers (11,15,32,35,39,40,60,62), CRC miss rates -seven papers (15,35,36,…”

Colonoscopy in the very elderly: a review of 157 cases

“…Colonoscopy is an important tool for the diagnosis and surveillance of colonic neoplasms and for the treatment of appropriately selected lesions [14]. Numerous publications have documented the benefits of colonoscopy [2,11,12,16,22,23], however, only a few have discussed its value in the elderly [5,17,18,24].…”

Screening Colonoscopy in Chinese and Western Patients: A Comparative Study

“…These results are consistent with previous longitudinal feasibility studies. For example, a study from China followed 2,196 asymptomatic elderly patients screened with frequent colonoscopies over 6 yr (27); during this period, 52 cancers and 5,801 adenomas were found. The complication rate (0.05%) and cecal intubation rate (98.9%) were quite acceptable.…”