Color Doppler ultrasonographic evaluation of renal cell carcinoma metastasis to the gallbladder.

Gallbladder’s clear cell renal carcinoma metastasis: A case report

“…A CT scan signal which could be of some help in differentiating between primary and metastatic gallbladder tumors is represented by the invasion of the mucosal layer; in case the mucosa is not infiltrated, indicating an invasion from the serosa layer, the primary gallbladder tumor can be excluded [11] . Doppler ultrasonography has been successful in demostrating the vascularity of renal cell carcinoma in other locations [17] .…”

Gallbladder Metastasis from Renal Cell Carcinoma

“…However, the number of clinical cases reported so far does not exceed 20. Furthermore, there have only been 10 cases, including this one, in which the metastasis did not involve any organs other than the gallbladder [4,5,6,7,8,9,10,11]. In all cases, the histological type was clear cell carcinoma.…”

Gallbladder’s Clear Cell Renal Cell Carcinoma Metastasis: A Systematic Review of the Literature

“…Metastatic spread to the gallbladder from intra-and extra-abdominal organs carcinomas has been reported previously, usually the metastatic lesion appears as an extraluminal mass due to peritoneal seeding or direct invasion. An intraluminal metastasis, is most likely hematogenous in origin, and has been reported from primary sites such as the skin, breast, lungs, esophagus, and kidney [15] .…”

“…It is widely accepted that metastasis to the gallbladder from extra-abdominal organs are by way of the hematogenous embolic route [13][14][15][16][17][18][19][20] , while intraperitoneal organs' metastases emerge either by deposition on the serosa surface of the gallbladder, or by peritoneal implantation, or by direct invasion of the gallbladder [20] . Gallbladder metastases have been reported from other primary tumors, melanoma being the most frequent, followed by lung, esophagus, pancreas and colon carcinoma [26-36-42] .…”