Color Doppler Ultrasound and Hemodynamics for Evaluating Graft Dysfunction in Recurrent Immunoglobulin A Nephropathy

Zeng, Jin; Chen, Guodong; Qiu, Jian; Tan, Yang; Liu, Guochang; Chen, Lizhong; Jia, Wei; Fu, Wen; Wang, Changxi

doi:10.12659/aot.931736

Cited by 2 publications

(1 citation statement)

References 22 publications

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“…Normally, renal cortex has lower echogenicity than normal liver and spleen. In Zhang et al.’s opinion, hyperechoic is a typical feature of graft dysfunction [ 27 ]. Echo changes because of the increasing glomerulosclerosis and TA/IF.…”

Section: Discussionmentioning

confidence: 99%

Noninvasive evaluation of IgA nephropathy fibrosis using Doppler ultrasound

Qin

Williams

2022

Renal Failure

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In this study, we aimed to explore the clinical value of routine color ultrasound parameters in the evaluation of tubular atrophy and interstitial fibrosis (TA/IF) in IgA nephropathy (IgAN). We enrolled 725 patients with IgAN who underwent renal biopsy at the First Affiliated Hospital of Anhui Medical University between January 2019 and May 2022. Examinations were performed to measure the routine ultrasound renal parameters and renal biopsy was done within next three days. Univariate and multivariate analyses were used to determine the correlates and the independent predictors of TA/IF. Simultaneously, a nomogram based on risk indicators was created to predict TA/IF. Univariate and multivariate analyses showed that sex ( p < 0.001, OR = 2.538, 95%CI: 1.739–3.734), renal length ( p < 0.001, OR = 0.927, 95%CI: 0.905–0.95), resistive index of main renal artery ( p = 0.037, OR = 1.891, 95%CI: 1.027–3.426), peak systolic velocity of segmental renal artery ( p = 0.58, OR = 0.975, 95%CI: 0.399–0.841), and cortex echogenicity ( p < 0.001, OR = 3.448, 95%CI: 2.382–5.018) were independent predictors of TA/IF in IgAN nomograms, with a good C -index of 0.765 (95%CI = 0.727–0.803). Analyses of the calibration charts show that nomograms have good performance and clinical applicability. In our study, renal color ultrasound parameters correlated well with TA/IF in IgAN. By establishing a conventional color ultrasound prediction model, we can accurately gauge the extent of TA/IF in patients with IgAN for clinical applications.

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Section: Discussionmentioning

confidence: 99%

Noninvasive evaluation of IgA nephropathy fibrosis using Doppler ultrasound

Qin

Williams

2022

Renal Failure

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Aerobic Training and Ointment Effect on range of motion, von Willebrand factor, vascular endothelial factor and Femoral Artery Hemodynamics in Joint Contracture: A Rat Model

Maimaiti,

Shu,

Miao

et al. 2024

Biological Research For Nursing

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Objective Using a rat model, we investigated the effect of multidisciplinary rehabilitation, including aerobic training and ointment, on the ROM, vWF, VEGF content, and femoral artery hemodynamics in rats with joint contracture. Methods A total of 44 Wistar rats were divided into the normal control group (NC, eight rats) and the experimental group (EG). A joint contracture model was established for the rats in the EG group by an external fixator. After fixator removal, 32 rats are further divided into the MC, SC, RE, and SR groups ( n = 8). Before and after the 42 day intervention, the ROM, vWF, VEGF, PS, ED, and RI were measured using X-ray imaging, ELISA, and color Doppler ultrasound, respectively. Results After fixator removal, ROM for EG group was lower than that of the NC group ( p < .01). After the intervention, ROM for the SR, RE, and SC groups was improved. The ROM for the SR group reached a similar value for NC group. vWF and VEGF levels in SR group were lower than in the MC, SC, and RE groups ( p < .05), and had a similar value to the NC groups. PS value for SR and RE groups was higher than the MC and SC groups. The RI value for SR group was higher than that of NC and MC groups. Conclusion Multidisciplinary rehabilitation used in this study can treat joint contracture synergistically. It improves the ROM of the joint, reduces the content of vWF and VEGF, and improves the femoral artery hemodynamics.

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Color Doppler Ultrasound and Hemodynamics for Evaluating Graft Dysfunction in Recurrent Immunoglobulin A Nephropathy

Cited by 2 publications

References 22 publications

Noninvasive evaluation of IgA nephropathy fibrosis using Doppler ultrasound

Noninvasive evaluation of IgA nephropathy fibrosis using Doppler ultrasound

Aerobic Training and Ointment Effect on range of motion, von Willebrand factor, vascular endothelial factor and Femoral Artery Hemodynamics in Joint Contracture: A Rat Model

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