Color/power Doppler sonographic differential diagnosis of superficial lymphadenopathy: metastasis, malignant lymphoma, and benign process.

Shirakawa, Toshiaki; Miyamoto, Yukio; Yamagishi, Jiro; Fukuda, Kunihiko; Tada, Shimpei

doi:10.7863/jum.2001.20.5.525

Cited by 39 publications

(32 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…On the contrary, most malignant nodes (78 %) show aberrant vessels with curved course entering from the nodal capsule, in addition to hilar vessels (mixed capsular±hilar vascularity; Fig. 19, 20) [59]. The amount of extrahilar vessels is higher in metastatic nodes than in lymphomatous nodes, which is likely due to different angiogenesis.…”

Section: Neck Lymph Nodesmentioning

confidence: 96%

Ultrasound of thyroid, parathyroid glands and neck lymph nodes

Solbiati

Osti²,

Cova³

et al. 2001

Eur Radiol

215

133

View full text Add to dashboard Cite

In the past 15 years high-frequency B-mode sonography and colour-power Doppler have become the most important and most widely employed imaging modalities for the study of the neck, in particular for thyroid gland, parathyroids and lymph nodes. Sonography allows not only the detection but often also the characterization of the diseases of these organs, distinguishing benign from malignant lesions with high sensitivity and specificity, which could be further improved by the employ of ultrasound contrast agents and harmonic imaging. Although no single sonographic criterion is specific for benign or malignant nature of the lesions, the combination of different signs can be markedly helpful to speed up the diagnostic process. Fine-needle aspiration biopsy (FNAB) remains the most accurate modality for the definitive assessment of thyroid gland nodules and of any doubtful case of nodal disease. In association with clinical findings and serum levels of parathormone, FNAB has specificity close to 100% for the characterization of parathyroid adenomas. A combined approach with sonography and FNAB is generally highly effective.

show abstract

Section: Neck Lymph Nodesmentioning

confidence: 96%

Ultrasound of thyroid, parathyroid glands and neck lymph nodes

Solbiati

Osti²,

Cova³

et al. 2001

Eur Radiol

215

133

View full text Add to dashboard Cite

show abstract

“…The role of doppler ultrasound in the evaluation of metastatic nodes is based on the fact that tumours larger than a few millimeters in diameter stimulate the growth of new vessels [7,8]. This tumour neovascularity has certain characteristics that enable a presumptive diagnosis of 1.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Colour Doppler Ultrasound in Diagnosis of Cervical Lymphadenopathy

Naik

Pai

Guruprasad

et al. 2012

J. Maxillofac. Oral Surg.

View full text Add to dashboard Cite

Objectives The purpose of the study was to evaluate the efficacy of colour doppler ultrasound (CDUS) in diagnosis of cervical lymphadenopathy. Materials and MethodsThe study group consisted of 30 patients with clinical evidence of cervical lymphadenopathy (19 patients with clinically suspected reactive/benign cervical lymphadenopathy and 11 patients with clinically suspected malignant/metastatic cervical lymphadenopathy). CDUS examinations were carried out for one lymph node (LN) in each patient and fine needle aspiration cytology of the same LN was obtained. To evaluate the efficacy of CDUS, comparison between clinical features, CDUS features and cytological features of enlarged cervical LNs were then done. Results Clinical examination evaluated 54 cervical LNs. CDUS evaluation discovered an additional 55 LNs (54 ? 55 = 109). Accuracy of the CDUS examination was higher than clinical evaluation. Patterns of colour doppler flow signals when correlated with cytological diagnosis showed central flow for benign nodes and peripheral flow for malignant nodes. The mean pulsatility index (PI) was 1.977 ± 0.669 in LNs involved with metastases and 0.839 ± 0.135in LNs affected by benign processes. LNs involved with metastases showed a characteristic high resistive index (RI) and a high pulsatility index than the lymph nodes affected by benign processes. The RI and PI were significantly different between LNs affected by benign versus malignant disease. Conclusion Nodal vascularity of the LNs can be used to differentiate benign from malignant lymphadenopathy. CDUS can be trusted upon as a reliable marker for the diagnosis of cervical lymphadenopathy.

show abstract

“…Other studies have also reported a similar central perfusion pattern of lymphomatous nodes [12,13]. In contrast, metastatic nodes show the presence of peripheral subcapsular vessels which access lymph nodes through afferent lymphatic vessels and invade marginal sinuses.…”

Section: Sonographymentioning

confidence: 71%