2023
DOI: 10.1590/0102-672020230053e1771
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Colorectal Cancer: Histopathological Profile and Prevalence of Dna Repair System Deficiency in Patients Submitted to Surgical Treatment in a University Hospital

Julia Werner de Oliveira,
Raquel Aguirra de Moraes,
Samya Hamad Mehanna
et al.

Abstract: BACKGROUND: Part of colorectal cancer cases occurs due to modifications in the DNA mismatch repair system, which are responsible for microsatellite instability. This alteration results in an unconventional phenotypic pattern of colorectal cancer. AIMS: To describe the epidemiological, histopathological and molecular profiles of patients with colorectal cancer who underwent surgical treatment in a reference hospital. METHODS: This is a cross-sectional, retrospective study with a quantitative approach, that in… Show more

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