“…The primary reason is, compared to western population, the colon cancer occurrence is less (but the numbers are increasing in the recent past years) and CTC as a diagnostic procedure is rare when compared to Colonoscopy. Secondary reasons are variations in the sensitivity and specificity decisions, differences of opinion (Mohandas, 2011), less number of experts to evaluate the ground truths, lack of references from Gastroenterology (we came to know this when discussed with few diagnostic centers) and the expensive diagnosis cost (Nair et al, 2013, have discussed about the cost of diagnosis, the difficulties in curing cancers due to late stage diagnosis and treatment of cancer in Indian hospitals). There has not been much statistics about usage of CTC in Indian hospitals, how many diagnostic centers have got this facility commissioned?…”