Colorectal cancer in nonagenarians

Abstract

Our results indicate that elective and emergency colorectal surgery can be performed with acceptable rates of mortality and morbidity on nonagenarian patients in good general condition with low perioperative risk. The 5-year survival rate was related to ASA grade and to the use of surgery.

Colorectal Cancer Surgery in the Very Elderly: Nonagenarians

“…this percentage imbalance is expected to increase in coming years, as the life expectancy gains for women continue to outpace men. 4 all but 1 (97.9%) of our patients had associated comorbidities, which is higher than previous similar studies, 9,17,18 but may reflect the increasing preparedness for clinicians to treat older and more infirm patients. our proportion of elective patients (79.2%) was much higher than other studies and may reflect in the low perioperative morbidity and mortality rates.…”

Complications and risk prediction in treatment of elderly patients with rectal cancer

“…The conflicting results may be a result of selection bias as there are no randomised controlled trials addressing the question. There is evidence that sub-groups of the elderly tolerate surgery as well as their younger counterparts [2,7], and several variables are highly relevant when deciding upon treatment.…”

“…Although both surgical and oncological treatment have become more differentiated, major surgery is still the cornerstone of rectal cancer treatment. There is evidence that elderly people should not be denied surgical treatment on the basis of their chronological age alone [2][3][4], but the consequences of complications are more often severe [5]. In clinical practice, elderly patients receive less curative surgery, less radiochemotherapy and often modified surgical treatment when operated [6], and no consensus on the treatment of elderly patients exists [7].…”

Emergency Surgery for Colorectal Cancer in Patients Aged Over 90 Years: Review of the Recent Literature

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derly people; approximately 60% of patients are aged >70 years at time of diagnosis and 43% of cases are aged >75 years in the western countries [1][2][3] . These proportions will likely continue to increase in the near future, because of the increasing percentage of people living past ninety years, a phenomenon associated with the aging world population.

In Italy, according to the Italian National Institute of Statistics (ISTAT) data, the population aged 85 and older will increase from 2.8% in 2011 to 7.8% in 2050, reaching an average life expectancy of 85.3 years for males and 90.5 years for females.

This highly significant demographic change in modern society has an important impact on health care, especially in cancer care, as cancer in people aged over 90, poses an ethical dilemma for surgeons and oncologists: non operative management or medical and/or surgical treatment?

…”

“…derly people; approximately 60% of patients are aged >70 years at time of diagnosis and 43% of cases are aged >75 years in the western countries [1][2][3] . These proportions will likely continue to increase in the near future, because of the increasing percentage of people living past ninety years, a phenomenon associated with the aging world population.…”