Colorectal cancer screening among obese versus non-obese patients in primary care practices

Ferrante, Joan M.; Ohman‐Strickland, Pamela; Hudson, Shawna V.; Hahn, Karissa A.; Scott, Jewel; Crabtree, Benjamin F.

doi:10.1016/j.cdp.2006.09.003

Cited by 87 publications

(87 citation statements)

References 57 publications

(57 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Interaction analyses with other environmental factors revealed that, among the combinations above, ATGCGT was the one that predisposed the most to CRC, as it was the only one found to be additionally associated with a perceptible increase in the risk of CRC in obese individuals (f14.4% of the study population). This last observation is a good example of gene-environment interaction: In a way, the genetic background seems to exacerbate the procarcinogenic effect of the environmental factor, because, in our cohorts, obesity alone was not found to be associated with an increased CRC risk as reported in the literature (41). On the other hand, genetic expression seems to be influenced by environmental factors, as independent analysis of the ATGCGT combination showed no association with CRC risk.…”

Section: Discussionsupporting

confidence: 70%

Combinations of Cytochrome P450 Gene Polymorphisms Enhancing the Risk for Sporadic Colorectal Cancer Related to Red Meat Consumption

Küry

Bruno

Robiou-du-Pont

et al. 2007

Cancer Epidemiology, Biomarkers &Amp; Prevention

View full text Add to dashboard Cite

Susceptibility to sporadic colorectal cancers (CRC) is generally thought to be the sum of complex interactions between environmental and genetic factors, all of which contribute independently, producing only a modest effect on the whole phenomenon. However, to date, most research has concealed the notion of interaction and merely focused on dissociate analyses of risk factors to highlight associations with CRC. By contrast, we have chosen a combinative approach here to explore the joint effects of several factors at a time. Through an association study based on 1,023 cases and 1,121 controls, we examined the influence on CRC risk of environmental factors coanalyzed with combinations of six single nucleotide polymorphisms located in cytochrome P450 genes (c.À163A>C and c.1548T>C in CYP1A2, g.À1293G>C and g.À1053C>T in CYP2E1, c.1294C>G in CYP1B1, and c.430C>T in CYP2C9). Whereas separate analyses of the SNPs showed no effect on CRC risk, three allelic variant combinations were found to be associated with a significant increase in CRC risk in interaction with an excessive red meat consumption, thereby exacerbating the intrinsic procarcinogenic effect of this dietary factor. One of these three predisposing combinations was also shown to interact positively with obesity. Provided that they are validated, our results suggest the need to develop robust combinative methods to improve genetic investigations into the susceptibility to CRC. (Cancer Epidemiol Biomarkers Prev 2007;16(7):1460 -7)

show abstract

Section: Discussionsupporting

confidence: 70%

Combinations of Cytochrome P450 Gene Polymorphisms Enhancing the Risk for Sporadic Colorectal Cancer Related to Red Meat Consumption

Küry

Bruno

Robiou-du-Pont

et al. 2007

Cancer Epidemiology, Biomarkers &Amp; Prevention

View full text Add to dashboard Cite

show abstract

“…Previous research has suggested that body image avoidance, especially for women, is related to lower quality of life (Cash et al, 2005), greater health risk, and decreased involvement in a variety of life events (Feingold & Mazzella, 1998;Ferrante, Ohman-Strickland, Hudson, Hahn, Scott, & Crabtree, 2006;Latner, 2008;Ostbye et al, 2005). Data for the current study was extracted from a largescale, internet-based survey on how size and body image predict avoidance behaviors in mainly overweight and obese, adult agerepresentative U.S. women and men of varying ethnicities.…”

Section: Discussionmentioning

confidence: 99%

Body size dissatisfaction and avoidance behavior: How gender, age, ethnicity, and relative clothing size predict what some won’t try

Maphis¹,

Martz²,

Bergman³

et al. 2013

Body Image

View full text Add to dashboard Cite

Sixty-eight percent of U.S. adults are overweight/obese, and this epidemic has physical, psychosocial, and behavioral consequences. An internet sample of adults (N = 2997) perceiving themselves as larger than ideal in clothing size reported their body mass index (BMI), relative clothing size (RS; discrepancy between current and ideal size), and avoidance behaviors. Exploratory factor analysis of 10 avoid-ance items produced social avoidance and body display avoidance factors. A relative importance analysis revealed RS as a better predictor than BMI for avoidance. A hierarchical multivariate analysis of covariance found RS to predict both avoidance constructs. The relationship between RS and both avoidance con-structs was stronger for women than men, and for younger as compared to older participants. Caucasians reported more body display avoidance than African Americans. This suggests that personal dissatisfac-tion with body size may deter involvement in varied life events and that women are especially avoidant of activities that entail displaying their bodies.

show abstract

“…Obese individuals, for example, might be less likely than non--obese persons to be screened for colorectal and breast cancer (Eichholzer et al, 2015;Ferrante et al, 2006) even though the evidence is not consistent.…”

Section: Observed In Their Cross--sectional Analysis Of Data From Thementioning

confidence: 99%

Lifestyle and health-related predictors of cervical cancer screening attendance in a Swiss population-based study

Richard

Rohrmann

Schmid

et al. 2015

Cancer Epidemiology

View full text Add to dashboard Cite

BACKGROUND: Since the implementation of cervical cancer (CC) screening, incidence and mortality rates have decreased worldwide. Little is known about lifestyle and health-related predictors of cervical cancer screening attendance in Switzerland. Our aim was to examine the relationship between lifestyle and health-related factors and the attendance to CC screening in Switzerland. METHODS: We analyzed data of 20-69 years old women (n=7319) of the Swiss Health Survey (SHS) 2012. Lifestyle factors included body mass index, smoking status, alcohol consumption, physical activity and attention to diet. Health-related factors of interest were diabetes, hypertension, high cholesterol levels, chronic diseases, self-perceived health, and psychological distress. We performed multivariable logistic regression analyses with the dichotomized CC screening status as outcome measure and adjusted for demographic factors. RESULTS: Obesity, low physical activity, and not paying attention to diet were statistically significantly associated with lower CC screening participation. High cholesterol levels and history of chronic diseases were statistically significantly positively associated with screening participation. CONCLUSION: Being obese, physically inactive and non-attention to diet are risk factors for CC screening attendance. These findings are of importance for improving the CC screening practices of low-user groups. AbstractBackground: Since the implementation of cervical cancer (CC) screening, incidence and mortality

show abstract

Colorectal cancer screening among obese versus non-obese patients in primary care practices

Abstract: BACKGROUND-Obesity is associated with increased colorectal cancer incidence and mortality. Previous studies using telephone survey data showed that obese women were less likely to receive colorectal cancer screening. It is unknown if this is true among patients in primary care practices.

Cited by 87 publications

References 57 publications

Combinations of Cytochrome P450 Gene Polymorphisms Enhancing the Risk for Sporadic Colorectal Cancer Related to Red Meat Consumption

Combinations of Cytochrome P450 Gene Polymorphisms Enhancing the Risk for Sporadic Colorectal Cancer Related to Red Meat Consumption

Body size dissatisfaction and avoidance behavior: How gender, age, ethnicity, and relative clothing size predict what some won’t try

Lifestyle and health-related predictors of cervical cancer screening attendance in a Swiss population-based study

Contact Info

Product

Resources

About