Colorectal cancer screening is cost-effective in the elderly who have had less intense prior screening, high baseline risk of colorectal cancer and less comorbidities

“…In a large screening trial in 884 patients, capsule colonoscopy had 88% sensitivity for detecting screening ( 114 ). Screening remains cost-eff ective in patients into their mid-80s if they have few comorbidities and limited prior screening ( 115,116 ).…”

Section: Capsule Colonoscopymentioning

confidence: 99%

Colorectal Cancer Screening: Recommendations for Physicians and Patients from the U.S. Multi-Society Task Force on Colorectal Cancer

Rex

Boland

Dominitz

et al. 2017

American Journal of Gastroenterology

530

266

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“…This national programme commenced in 2006, and initially, only people turning 55 and 65 years old each year were invited to participate and sent a kit for faecal occult blood testing (FOBT). In 2008, this programme was extended to people in the year they turned 50 years and in 2013 to people turning 60 years (Jenkins, 2016). From 2015 (after the end of follow-up in this study), the programme was extended to people aged from 50 years up to 74 years.…”

Section: Defining Exposurementioning

confidence: 99%

Colorectal, cervical and prostate cancer screening in Australians with severe mental illness: Retrospective nation-wide cohort study

Tuesley

Jordan

Siskind

et al. 2018

Aust N Z J Psychiatry

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Objective: People with severe mental illness have similar cancer incidence, but higher mortality than the general population. Participation in cancer screening may be a contributing factor but existing studies are conflicting. The aim of this study was to investigate the frequency of colorectal, prostate and cervical cancer screening among people with and without severe mental illness in Australia, who have access to universal health care. Methods: We followed three cohorts using de-identified data from a random 10% sample of people registered for Australia's universal health care system: those aged 50-69 years (n = 760,058) for colorectal cancer screening; women aged 18-69 years (n = 918,140) for cervical cancer screening and men aged 50-69 years (n = 380,238) for prostate cancer screening. We used Poisson regression to estimate incidence rate ratios and 95% confidence intervals for the association between severe mental illness and rates of faecal occult blood testing, pap smears and prostate-specific antigen testing. Results: Having severe mental illness was associated with a 17% reduction in rates of pap smear (incidence rate ratio = 0.83, 95% confidence interval: 0.82-0.84) and prostate-specific antigen testing (incidence rate ratio = 0.83, 95% confidence interval: 0.81-0.85), compared to the general population. By contrast, incidence rates of faecal occult blood testing were only lower in people with severe mental illness among the participants who visited their general practitioner less than an average of five times per year (incidence rate ratio = 0.83, 95% confidence interval = [0.73, 0.94]). Conclusion: Our results suggest that differences in screening frequency may explain some of the mismatch between cancer incidence and mortality in people with severe mental illness and indicate that action is required to improve preventive screening in this very disadvantaged group.

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Colorectal cancer screening is cost-effective in the elderly who have had less intense prior screening, high baseline risk of colorectal cancer and less comorbidities

Cited by 5 publications

References 4 publications

Colorectal cancer screening: Recommendations for physicians and patients from the U.S. Multi-Society Task Force on Colorectal Cancer

Colorectal cancer screening: Recommendations for physicians and patients from the U.S. Multi-Society Task Force on Colorectal Cancer

Colorectal Cancer Screening: Recommendations for Physicians and Patients from the U.S. Multi-Society Task Force on Colorectal Cancer

Colorectal, cervical and prostate cancer screening in Australians with severe mental illness: Retrospective nation-wide cohort study

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