Colorectal carcinoma in the first decade of life: a systematic review

Abstract

In children, colorectal carcinoma presents distinctive characteristics, which determines poor survival.

Gastrointestinal tract carcinoma in pediatric and adolescent age: The Italian TREP project experience

“…The poor prognosis for GI tract carcinomas in pediatric age is largely related to the high incidence of aggressive histotypes, but other factors contribute to this issue . For a start, there is the difficulty of arriving at an early diagnosis of sporadic tumors in this time of life.…”

Targeting Epidermal Growth Factor Receptor (EGFR) in Pediatric Colorectal Cancer

“…Carcinoma of the large bowel is extremely rare in the pediatric age group [10]. It accounts for about 2% of all malignancies in patients aged 15 to 29 years [11].…”

“…Histologically, CRC of the pediatric and adolescent age (pCRC) shows a higher incidence of mucinous adenocarcinoma (40-50%), frequently with the signet ring cell type [10,12,15,17,18]. Tumors with such histology arise from the surface of the intestine, usually at the site of an adenomatous polyp.…”

Colorectal cancer in pediatric age: case report

“…Se describió en todas las franjas etarias infantiles incluso en el recién nacido, pero los de la segunda década de edad parecen los más afectados. Entre los 0-9 años, su frecuencia es 0.4-0.9% y el sexo- (9)(10)(11) ratio es 2.2:1 .…”