Colorectal Neuroendocrine Neoplasm Detection Rate During Colonoscopy: Results From Large-Scale Data of Colonoscopies in Japan

Abstract

Introduction: This study investigated the detection rate of colorectal neuroendocrine neoplasms (NENs) using large-scale colonoscopy data. Methods: This cross-sectional analysis used large-scale data from a Japanese multicenter observational study of colonoscopies performed from 2010 through 2020. Results: Among 82,005 colonoscopy cases, colorectal NENs were identified in 71 (67 of which were neuroendocrine tumors), with a detection rate of 0.087% (95% confidence interval: 0.069–0.109). Most were small rectal lesions, with only four >10 mm in size and three located in the colon. Discussion: The detection rate of colorectal NENs during colonoscopy is substantially higher than expected. Trial registration: This study was registered in the University Hospital Medical Information Network as UMIN000040690 (https://center6.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000046442).