Colorimetric and fluorescent probe for real-time detection of palladium (II) ion in aqueous medium and live cell imaging

A Pyridinyl‐Pyrazole BODIPY as Lipid Droplets Probe

“…Finally, the HRMS analysis provided further insight into the formation of the 1:1 complex between LdBD‐1 and Pd 2+ (Supporting Information Figure S11). In previous studies, LC–MS trace of probe‐ Pd 2+ complex come together with counter anion 30‐32 . After the addition of Pd 2+ , we also found a peak at 609.1653 (m/z calculated for [LdBD‐1+ Pd 2+ + Cl − ] + = 609.0889) confirming the formation of the 1:1 complex between LdBD‐1 and Pd 2+ .…”

“…In previous studies, LC-MS trace of probe-Pd 2+ complex come together with counter anion. [30][31][32] After the addition of Pd 2+ , we also found a peak at 609.1653 (m/z calculated for [LdBD-1+ Pd 2 + + Cl − ] + = 609.0889) confirming the formation of the 1:1 complex between LdBD-1 and Pd 2+ .…”

Coumarin-Based Small-Molecule Fluorescent Chemosensors

“…While Pd 2+ induced an approximately 6-fold fluorescence reduction, other metal cations did not induce a fluorescence change. A similar Pd 2+ -induced fluorescence quenching was also observed in 175 – 177 . − While 175 and 177 showed no significant interference from other metal cations, the fluorescence quenching effect was reduced in the presence of Hg 2+ for probe 176 .…”

Orange-Emissive Sulfur-Doped Organosilica Nanodots for Metal Ion/Glutathione Detection and Normal/Cancer Cell Identification

“…In recent years, developing smart sensors with versatile sensing capabilities and high sensitivity has drawn much interest from the biosensing community. − Various sensing platforms have been developed for the efficient detection of different metal elements, which may have the positive and/or negative effects on human bodies. Specifically, Fe and Cu are the essential elements of the human body for numerous physiological and pathological functions. − The Bi element has been extensively used for radiotherapeutic, antibacterial, antiulcer, and anti-human immunodeficiency virus (anti-HIV) treatments. , However, abnormal contents of Fe, Cu, or Bi usually cause various diseases, such as anemia, hepatitis, Wilson’s/Alzheimer’s/Parkinson’s disease, or even cancer. − For Ag, its excessive content in the body will lead to severe skin problems, stomach pain, nervous system damage, and even death. − For Pd, the excess intake of this element will badly affect various cellular processes and result in severe physiological disorders. , In addition, Hg poisoning in living organisms is still a hot issue of global concern, as Hg 2+ can easily penetrate biological membranes and cause toxicity. , Considering that various metal-sensing platforms can only detect limited types of metal ions, − it is desirable to develop a multifunctional sensing platform for achieving the simultaneous and efficient detection of different types of metal ions to well meet the increased requests of clinical diagnosis and sanitation monitoring systems.…”

“…15−17 For Pd, the excess intake of this element will badly affect various cellular processes and result in severe physiological disorders. 18,19 In addition, Hg poisoning in living organisms is still a hot issue of global concern, as Hg 2+ can easily penetrate biological membranes and cause toxicity. 20,21 Considering that various metal-sensing platforms can only detect limited types of metal ions, 22−24 it is desirable to develop a multifunctional sensing platform for achieving the simultaneous and efficient detection of different types of metal ions to well meet the increased requests of clinical diagnosis and sanitation monitoring systems.…”