“…[44][45][46] Recently, we have reported on a simple acyclic salen Schiff base showing selective fluorescence turn-on response for the detection of Zn(II) ions in the nanomolar range, which is employed for confocal fluorescence microscopic imaging in HeLa cells. 47 Recognizing the importance of this hot research topic, many notable reviews have been published, [48][49][50] focusing on classifying fluorophore combinations rather than differentiating metal ion analytes. This review examines the recent advances in the development of Schiff base-based fluorescent turn-on chemosensors, including synthesis, design principle with photophysical properties, sensing mechanism, and analyte recognition studies with many parameters, primarily emphasizing on biological applications.…”