Colorimetric aptasensors for determination of tobramycin in milk and chicken eggs based on DNA and gold nanoparticles

Ma, Qiang; Wang, Yuxian; Jia, Jinsheng; Xiang, Yuhong

doi:10.1016/j.foodchem.2018.01.022

Cited by 142 publications

(52 citation statements)

References 36 publications

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“…The STE is an exceedingly essential part of an aptasensor while designing colorimetric assays with AuNPs because of their special optical properties, e.g., high extinction coefficient and surface plasmon resonance (SPR) [48]. The aptamers are adsorbed on AuNPs surface (in the absence of their high-affinity target) to stabilize them, thus preventing their salt-induced aggregation because of SPR connection among adjoining particles [49]. Contrarily, on target addition to the aptasensor, aptamer binds to their high affinity target, causing aptamer desorption from AuNPs surface, thus aggregating the AuNPs leading to a color change from bright red to blue or purple (Figure 1D) most commonly (the absorbance peak shifts from 520 to 650 nm) because their unique localized surface plasmon resonance (LSPR) is changed.…”

Section: Gold Nanoparticles (Aunps) Based Colorimetric Aptasensorsmentioning

confidence: 99%

Advances in Gold Nanoparticles-Based Colorimetric Aptasensors for the Detection of Antibiotics: An Overview of the Past Decade

Zahra

Ali

et al. 2021

Nanomaterials

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Misuse of antibiotics has recently been considered a global issue because of its harmful effects on human health. Since conventional methods have numerous limitations, it is necessary to develop fast, simple, sensitive, and reproducible methods for the detection of antibiotics. Among numerous recently developed methods, aptasensors are fascinating because of their good specificity, sensitivity and selectivity. These kinds of biosensors combining aptamer with colorimetric applications of gold nanoparticles to recognize small molecules are becoming more popular owing to their advantageous features, for example, low cost, ease of use, on-site analysis ability using naked eye and no prerequisite for modern equipment. In this review, we have highlighted the recent advances and working principle of gold nanoparticles based colorimetric aptasensors as promising methods for antibiotics detection in different food and environmental samples (2011–2020). Furthermore, possible advantages and disadvantages have also been summarized for these methods. Finally, the recent challenges, outlook, and promising future perspectives for developing novel aptasensors are also considered.

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Section: Gold Nanoparticles (Aunps) Based Colorimetric Aptasensorsmentioning

confidence: 99%

Advances in Gold Nanoparticles-Based Colorimetric Aptasensors for the Detection of Antibiotics: An Overview of the Past Decade

Zahra

Ali

et al. 2021

Nanomaterials

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“…Han et al [ 124 ] developed a magnetic bead-based SELEX to identify 37 ssDNA aptamers specific for tobramycin using a fluorescent method based on the reported principle by Ma’s team [ 125 ], in which they developed a colorimetric aptasensor for the determination of tobramycin in milk and chicken eggs based on the adsorption of ssDNA aptamers on the surface of AuNPs. With the sensor of Ma et al [ 125 ] the one reaching lowest LOD was developed ( Table 6 ).…”

Section: Aptasensors For Different Antibiotic Classesmentioning

confidence: 99%

Aptamer-Based Biosensors for Antibiotic Detection: A Review

2018

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Antibiotic resistance and, accordingly, their pollution because of uncontrolled usage has emerged as a serious problem in recent years. Hence, there is an increased demand to develop robust, easy, and sensitive methods for rapid evaluation of antibiotics and their residues. Among different analytical methods, the aptamer-based biosensors (aptasensors) have attracted considerable attention because of good selectivity, specificity, and sensitivity. This review gives an overview about recently-developed aptasensors for antibiotic detection. The use of various aptamer assays to determine different groups of antibiotics, like β-lactams, aminoglycosides, anthracyclines, chloramphenicol, (fluoro)quinolones, lincosamide, tetracyclines, and sulfonamides are presented in this paper.

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“…The employment of aptamers not only improves the detection specificity but also improves the detection sensitivity. The aptamer-based colorimetric sensing strategy has been developed for the detection of kanamycin, tobramycin, and neomycin with LODs of 8.1 nM, 23.1 nM, and 27 nM, respectively, in which the ratio A620/A520 was employed as the parameter for quantitative detection [55][56][57]. In order to improve the performance of the Au NP-based colorimetric aptasensor for the detection of antibiotics, Shayesteh's group employed a polyA-tailed aptamer and poly(diallyl dimethyl ammonium chloride) (PDDA) to replace the original aptamer and salt, respectively, and constructed a colorimetric assay for the detection of kanamycin ( Figure 5B).…”

Section: Based On Target-induced Aggregation Of Metal Nanoparticlesmentioning

confidence: 99%

Recent Advances in Optical Detection of Aminoglycosides

Zhou

Cao

2020

Applied Sciences

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Aminoglycosides (AGs) are broad-spectrum antibiotics used in both human infection and animal medicine. The overuse of AGs causes undesirable residues in food, leading to serious health problems due to food chain accumulation. In recent years, various methods have been developed to determine AGs in food. Among these methods, fluorescent (FL), colorimetric and chemiluminescent (CL) optical methods possess advantages such as their simple instrumentation, low cost, simple operation, feasibility of realizing visualization, and smartphone imaging. This mini-review summarizes optical assays for the detection of AGs in food developed in recent years. The detection principles for different categories are discussed. Then, the amplification techniques for the ultrasensitive detection of AGs are introduced. We also discuss multiplex methods for the simultaneous detection of AGs. Finally, the challenges and future prospects are discussed in the Conclusions and Perspectives section.

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Colorimetric aptasensors for determination of tobramycin in milk and chicken eggs based on DNA and gold nanoparticles

Cited by 142 publications

References 36 publications

Advances in Gold Nanoparticles-Based Colorimetric Aptasensors for the Detection of Antibiotics: An Overview of the Past Decade

Advances in Gold Nanoparticles-Based Colorimetric Aptasensors for the Detection of Antibiotics: An Overview of the Past Decade

Aptamer-Based Biosensors for Antibiotic Detection: A Review

Recent Advances in Optical Detection of Aminoglycosides

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