Colorimetric determination of some toxic metal ions in post-mortem biological samples

Shahat, Ahmed; Ali, E.A.; Shahat, M.F. El

doi:10.1016/j.snb.2015.07.032

Cited by 55 publications

(16 citation statements)

References 55 publications

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“…They are self-contained devices that can provide a measurable physical signal correlated with the chemical composition of the surrounding environment. Recently, the Zr-based metalorganic framework (UiO-66) or mesoporous TiO 2 as solid chemical carriers for dithizone (Dz) have been described for sensitive and selective discrimination of trace levels of some toxic metal ions such as Cu(II), Pb(II), Hg(II), and Cd(II) at 10 −9 mol/dm 3 in post-mortem biological samples (Shahat et al, 2013 ; Shahata et al, 2015 ).…”

Section: Discussionmentioning

confidence: 99%

“…This has changed drastically with the development of third-generation synchrotrons (USA [APS], France [ESRF], Japan [SPring8]) offering relevant spatial map resolution able to perform quantitative elemental imaging of hydrated biological specimens with submicron-resolution. Moreover, SXRF microscopy is able to provide information concerning the oxidation state of an element and even coordination environment (micro-XANES spectroscopy; Shahata et al, 2015 ). Synchrotron X-ray fluorescence technique is described precisely in the following research and review papers (James et al, 2011 ; Majumdaz et al, 2012 ; Pushie et al, 2014 ; Niemiec et al, 2015 ; Takano et al, 2017 ).…”

Section: Nuclear Methodsmentioning

confidence: 99%

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Analysis of Trace Elements in Human Brain: Its Aim, Methods, and Concentration Levels

et al. 2019

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Trace elements play a crucial role in many biochemical processes, mainly as components of vitamins and enzymes. Although small amounts of metal ions have protective properties, excess metal levels result in oxidative injury, which is why metal ion homeostasis is crucial for the proper functioning of the brain. The changes of their level in the brain have been proven to be a risk factor for Alzheimer's, Parkinson's, and Huntington's diseases, as well as amyotrophic lateral sclerosis. Therefore, it is currently an important application of various analytical methods. This review covers the most important of them: inductively coupled ground mass spectrometry (ICP-MS), flame-induced atomic absorption spectrometry (FAAS), electrothermal atomic absorption spectrometry (GFAAS), optical emission spectrometry with excitation in inductively coupled plasma (ICP-OES), X-ray fluorescence spectrometry (XRF), and neutron activation analysis (NAA). Additionally, we present a summary of concentration values found by different research groups.

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Section: Discussionmentioning

confidence: 99%

Section: Nuclear Methodsmentioning

confidence: 99%

Analysis of Trace Elements in Human Brain: Its Aim, Methods, and Concentration Levels

et al. 2019

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“…Nanostructured materials are powerful molecular tools for the analysis of many metal ions and anions . These materials are attracting much attention, owing to their high stability.…”

Section: Introductionmentioning

confidence: 99%

Development of nanomaterial chemosensors for toxic metal ions sensing

Fayed

El‐Nahass

El‐Daly

et al. 2019

Applied Organom Chemis

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Heavy metal ions are harmful to aquatic life and humans owing to their high toxicity and non-biodegradability, so their removal from wastewater is an important task. Therefore, this work focuses on designing suitable, simple and economical nanosensors to detect and remove these metal ions with high selectivity and sensitivity. Based on this idea, different types of mesoporous materials such as hexagonal SBA-15, cubic SBA-16 and spherical MCM-41, their chloro-functionalized derivatives, as well as 4-(4-nitro-phenylazo)naphthalen-1-ol (NPAN) azo dye have been synthesized, with the aim of designing some optical nanosensors for metal ions sensing applications. The mentioned azo dye has been anchored into the chloro-functionalized mesoporous materials. The designed nanosensors were characterized using scanning and transmission electron microscopy as well as Fourier transform infrared and UV-visible spectral analysis, nitrogen adsorption-desorption isotherms, low-angle X-ray diffraction and thermogravimetric analyses. Their optical sensing to various toxic metal ions such as Cd (II), Hg (II), Mn (II), Fe (II), Zn (II) and Pb (II) at different values of pH (1.1, 4.9, 7 and 12) was investigated. The optimization of experimental conditions, including the effect of pH and metal ion concentration, was examined. The experimental results showed that the solution pH had a major impact on metal ion detection. The optical nanosensors respond well to the tested metal ions, as reflected by the enhancement in both absorption and emission spectra upon adding different concentrations of the metal salts and were fully reversible on adding ethylene diamine tetra acetic acid or citric acid to the formed complexes. High values of the binding constants for the designed nanosensors were observed at pHs 7 and 12, confirming the strong chelation of different metals to the nanosensor at these pHs. Also, high binding constants and sensitivity were observed for NPAN-MCM-41 as a nanosensor to detect the different metal ions. From the obtained results, we succeeded in transforming the harmful azo dye into an environmentally friendly form via designing of the optical nanosensors used to detect toxic metal ions in wastewater with high sensitivity.

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“…Inductively coupled plasmas combined with either atomic emission spectroscopy or mass spectrometry are currently the methods of choice for very accurate and selective detection . Competing and more compact methods are based on colorimetric or fluorescence assays, X‐ray fluorescence, or protein binding assays and have made considerable progress, even though some still lack the selectivity or sensitivity required for water quality monitoring. In most countries, the concentration of lead in drinking water is not allowed to exceed 5–15 ppb, whereas levels exceeding 1 ppm have been reported in heavily contaminated tap water (1 ppb w = 4.83 × 10 −9 m ) .…”

Section: Introductionmentioning

confidence: 99%

Tetrasulfide‐Functionalized Mesoporous Silica on Nanowire Ring Resonators for Detection of Aqueous Lead, Pb(II)

Chen

Saunders

Borjian

et al. 2018

Advanced Sustainable Systems

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currently the methods of choice for very accurate and selective detection. [4] Competing and more compact methods are based on colorimetric [5] or fluorescence [6] assays, X-ray fluorescence, or protein binding assays and have made considerable progress, even though some still lack the selectivity or sensitivity required for water quality monitoring. In most countries, the concentration of lead in drinking water is not allowed to exceed 5-15 ppb, whereas levels exceeding 1 ppm have been reported in heavily contaminated tap water (1 ppb w = 4.83 × 10 −9 m). [7] In-line detection of heavy metals either at the water treatment plant or inside the distribution system is considered ideal to ensure safe drinking water. [8] Here, we report on a functionalized mesoporous silica film with a very high affinity to Pb(II) which was applied to a silicon-based microphotonic resonator as a refractive index sensing platform. This combination results in a compact and comparably simple sensor capable of detecting lead with high selectivity at ppb levels in water. Hundreds of these coated microresonators can be produced in a single fabrication run using a highly parallelized process, thereby reducing the cost considerably.Micro-/mesoporous silica materials (MPS) -in essence, very porous forms of glass -have been widely used in absorbing, scrubbing, and extracting analytes from liquids. [9][10][11][12] These processes exploit the large surface area of MPS materials. Their silica frame imparts good chemical resistance, high stiffness, and good optical properties. Mesoporous silica can be coated on waveguide surfaces using sol-gel methods and is compatible with silica-based optical waveguide sensors, such as long-period fiber gratings (LPG) [13] and silicon-on-insulator waveguide sensors. [14] Different functional groups can be added to the silica networks to bind selectively to a variety of analytes, including metal ions. [13,[15][16][17][18][19][20][21][22][23][24] Another large class of porous scrubbing materials is based on naturally derived low-cost materials such as cocoa pod husks, tea waste, dried sunflower leaves, etc., but these materials are unsuitable as refractive index sensor materials, since they are not optically transparent and cannot be readily applied to refractive index sensor platforms. [25] Previous research has shown that mesoporous silica functionalized with bis[3-(triethoxysilyl)propyl]tetrasulfide (BTESPT) Silicon-on-insulator (SOI) microring resonators coated with tetrasulfidefunctionalized mesoporous silica (MPS) (S 4 -MPS) are reported as sensors to detect Pb(II) ions in aqueous solutions from 10 ppb to 1 ppm. The sensors are based on the interaction of the evanescent field of the guided light with the functionalized mesoporous silica films. Upon absorption of metal ions, the resonant wavelengths of the microresonators shift due to the increased refractive index of the film. The sensors are exposed to aqueous solutions of Pb(II) ions at different concentrations and time-resolved absorption-desorption curves...

show abstract

Colorimetric determination of some toxic metal ions in post-mortem biological samples

Cited by 55 publications

References 55 publications

Analysis of Trace Elements in Human Brain: Its Aim, Methods, and Concentration Levels

Analysis of Trace Elements in Human Brain: Its Aim, Methods, and Concentration Levels

Development of nanomaterial chemosensors for toxic metal ions sensing

Tetrasulfide‐Functionalized Mesoporous Silica on Nanowire Ring Resonators for Detection of Aqueous Lead, Pb(II)

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