Colorimetric Sensor Arrays for the Detection and Identification of Chemical Weapons and Explosives

Kangas, Michael J.; Burks, Raychelle; Atwater, Jordyn; Lukowicz, Rachel; Williams, Pat Stephens; Holmes, Andrea E.

doi:10.1080/10408347.2016.1233805

Cited by 177 publications

(95 citation statements)

References 114 publications

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“…For various colorimetric devices for analysis, lateral flow tests (LFA) and paper devices are the main methods which are commonly associated with enzyme-linked immunosorbent assay (ELISA) to identify targets [38]. As mentioned earlier, these devices combined with MNPs have benefits such as sensitivity, specificity, speed, and inexpensive platforms [39]. Moreover, due to the small testing sample volume, vulnerable individuals being exposed to dangerous chemicals is not an issue.…”

Section: Colorimetric Biosensing Devicesmentioning

confidence: 99%

Magnetic Particles: Their Applications from Sample Preparations to Biosensing Platforms

et al. 2020

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The growing interest in magnetic materials as a universal tool has been shown by an increasing number of scientific publications regarding magnetic materials and its various applications. Substantial progress has been recently made on the synthesis of magnetic iron oxide particles in terms of size, chemical composition, and surface chemistry. In addition, surface layers of polymers, silica, biomolecules, etc., on magnetic particles, can be modified to obtain affinity to target molecules. The developed magnetic iron oxide particles have been significantly utilized for diagnostic applications, such as sample preparations and biosensing platforms, leading to the selectivity and sensitivity against target molecules and the ease of use in the sensing systems. For the process of sample preparations, the magnetic particles do assist in target isolation from biological environments, having non-specific molecules and undesired molecules. Moreover, the magnetic particles can be easily applied for various methods of biosensing devices, such as optical, electrochemical, and magnetic phenomena-based methods, and also any methods combined with microfluidic systems. Here we review the utilization of magnetic materials in the isolation/preconcentration of various molecules and cells, and their use in various techniques for diagnostic biosensors that may greatly contribute to future innovation in point-of-care and high-throughput automation systems.

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Section: Colorimetric Biosensing Devicesmentioning

confidence: 99%

Magnetic Particles: Their Applications from Sample Preparations to Biosensing Platforms

et al. 2020

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“…A promising technology to circumvent some of these disadvantages is the colorimetric sensors array (CSA), a sensitive and highly practical, low-cost approach based on naked-eye detection of organic/inorganic analytes or infective agents and their products alike. 21 Other contributions have reached the realms of electrical engineering, material science, and nanotechnology, e.g., the ultratrace detection of dangerous analytes. 22 Additionally, artificial organs such as chemical noses 23 and tongues 24 may replace specially trained sniffer dogs and bees/wasps for explosive detection.…”

Section: State Of the Art Explosives And Cbrn Detectionmentioning

confidence: 99%

Porphyrins in troubled times: a spotlight on porphyrins and their metal complexes for explosives testing and CBRN defense

2018

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“…To solve this problem, increasing attention has been paid to sensor arrays based on colorimetric assays . Colorimetric sensor array technology has been used to detect and differentiate brands of tea samples . Cross‐responsive sensor technology has been applied in the sensor array.…”

Section: Introductionmentioning

confidence: 99%

Sensitive chemical sensor array based on nanozymes for discrimination of metal ions and teas

Cheng

Huang

et al. 2019

Luminescence

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Tea, originating from China, is an important part of Chinese traditional culture. There are different qualities of and producing areas for tea on the market, therefore it is necessary to discriminate between teas in a fast and accurate way. In this study, a chemical sensor array based on nanozymes was developed to discriminate between different metal ions and teas. The indicators for the sensor array are three kinds of nanozymes mimicking laccase (Cu‐ATP, Cu‐ADP, Cu‐AMP). The as‐developed sensor array successfully discriminated 12 metal ions and the detection limit was as low as 0.01 μM. The as‐developed sensor array was also able to discriminate tea samples. Different kinds of tea samples appeared in different areas in the canonical score plot with different response patterns. Furthermore, in a blind experiment, we successfully discriminated 12 samples with a 100% accuracy. This sensor array integrates chemistry and food science together, realizing the simultaneous detection of several kinds of teas using a sensitive method. The as‐developed sensor array would have an application in the tea market and provide a fast and easy method to discriminate between teas.

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Colorimetric Sensor Arrays for the Detection and Identification of Chemical Weapons and Explosives

Cited by 177 publications

References 114 publications

Magnetic Particles: Their Applications from Sample Preparations to Biosensing Platforms

Magnetic Particles: Their Applications from Sample Preparations to Biosensing Platforms

Porphyrins in troubled times: a spotlight on porphyrins and their metal complexes for explosives testing and CBRN defense

Sensitive chemical sensor array based on nanozymes for discrimination of metal ions and teas

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