COLT-Viz: Interactive Visualization of Antibody Lineage Trees

Abstract

25Many tools have been developed to visualize phylogenetic trees, which is a traditional technique 26 for evolutionary tree analysis. However, due to the unique characteristics of antibody lineage 27 trees, the phylogenetic method cannot adequately construct proper tree structures for antibody antibody sequences, thus more dimensions need to be encoded in the tree structure visualization. 33Further, users may wish to manually adjust the tree structure for a special context. When doing 34 so, they may wish to maintain some biological constraints that are applicable in antibody lineage