COLUMBIA: 40 Million People Exposed to Extreme Ultraviolet Radiation During the Whole Year

Solórzano, Liban Horacio Madrigal; Hernández, Giovanna Saavedra; Jaramillo, Diva

doi:10.1093/oxfordjournals.rpd.a033230

Cited by 7 publications

(6 citation statements)

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“…It has been demonstrated that the Colombian population is exposed to high ultraviolet radiation during the whole year 9 . Even more worrisome, in a recent study we have identified extreme ultraviolet indexes (UVI) in Medellín (manuscript in preparation).…”

Section: Introductionsupporting

confidence: 93%

“…It has been demonstrated that the Colombian population is exposed to high ultraviolet radiation during the whole year. 9 Even more worrisome, in a recent study we have identified extreme ultraviolet indexes (UVI) in Medellín (manuscript in preparation). In spite of that fact, to date, skin cancer knowledge and protective behavior have not been evaluated, in a well-designed population study in our country.…”

Section: Introductionmentioning

confidence: 99%

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Impact of a sun protection campaign in Medellín (Colombia)

Sanclemente

2009

Int J Dermatology

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Section: Introductionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Impact of a sun protection campaign in Medellín (Colombia)

Sanclemente

2009

Int J Dermatology

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“…The highest reported UVI measurements in the Northern Hemisphere have been recorded at high altitudes. At over 2500 m above sea level, Bogota in Colombia has registered a UVI of 16 (36), and a UVI of 17 has been reported (R. McKenzie, personal communication) for Mauna Loa volcano in Hawaii at 3400 m above sea level.…”

Section: Resultsmentioning

confidence: 97%

Global Solar UV Index: Australian Measurements, Forecasts and Comparison with the UK^¶

Gies¹,

Roy²,

Javorniczky³

et al. 2004

Photochem & Photobiology

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The 2002 revision of the UV index (UVI) issued by the World Health Organisation (WHO), the World Meteorological Office (WMO), the United Nations Environment Programme (UNEP) and the International Commission on Non-Ionizing Radiation Protection (ICNIRP) (World Health Organization [2002] Global Solar UV Index: A Practical Guide. WHO, Geneva) was motivated by the need to further standardize the use and presentation of the UVI. Awareness of the hazards of solar UV radiation (UVR) is generally high in Australia, but more effective use of the UVI will assist in promoting further changes to the population's sun exposure behavior. UVI levels for a number of cities around Australia as measured by the Australian Radiation Protection and Nuclear Safety Agency (ARPANSA), covering the time period 1996-2000, are presented. Also shown are UVI forecasts from the Australian Bureau of Meteorology (BOM). Agreement between the BOM data and the measurements varies depending on the location but is within 2 UVI units approximately 75% of the time. UVI levels are supplied to the media, and in summer values in excess of 12-14 are regularly recorded, although the more northerly locations occasionally reach 16 and 17. The factors affecting the solar UVR environment and the measured UVI are also discussed and compared against measurements from the UK.

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“…The patient sample analyzed in this study lives in a mountainous area of the equatorial region, where the population is exposed to high solar radiation indices (index > 10) [ 22 ]. However, in this region, the melanoma incidence is low compared to other areas of the world [ 23 – 25 ].…”

Section: Discussionmentioning

confidence: 99%

Mutations in the BRAF, NRAS, and C‐KIT Genes of Patients Diagnosed with Melanoma in Colombia Population

Gutiérrez-Castañeda

Gamboa

Nova

et al. 2020

BioMed Research International

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Introduction. Mutations in the BRAF, NRAS, and C-KIT genes have been associated with the histopathological characteristics of melanoma. Likewise, the incidence of each of these subtypes changes according to the geographical origin of the population analyzed. Objective. To determine the mutation frequency in exons 11 and 15 of the BRAF gene, exons 1 and 2 of the NRAS gene, and exons 11, 13, and 17 of the C-KIT gene and to relate it with histological subtypes in patients from a region with high levels of ultraviolet radiation. Methodology. The clinicopathological characteristics of 54 cutaneous melanoma samples were analyzed. Mutation analysis was performed via qPCR on paraffin-embedded tumor tissue samples using probes specific for the V600E mutation. Amplification of exons 11 and 15 of the BRAF gene, exons 1 and 2 of the NRAS gene, and exons 11, 13, and 17 of the C-KIT gene was performed for subsequent sequencing using the Sanger method. Result. The most frequent histological subtype in the analyzed sample was lentigo maligna/lentigo maligna melanoma (52%) followed by acral lentiginous melanoma (20%). The BRAF-V600 variant was the most frequent (63.6%). The most frequent (54%) mutation in NRAS was p.Lys5∗. In the C-KIT gene, only the Val560Ala mutation was found. Conclusion. Differences in histological subtypes and mutations in the BRAF, NRAS, and C-KIT genes were found in the analyzed population. This indicates that environmental and genetic factors significantly influence the introduction of the disease in this geographic region.

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COLUMBIA: 40 Million People Exposed to Extreme Ultraviolet Radiation During the Whole Year

Cited by 7 publications

References 0 publications

Impact of a sun protection campaign in Medellín (Colombia)

Impact of a sun protection campaign in Medellín (Colombia)

Global Solar UV Index: Australian Measurements, Forecasts and Comparison with the UK^¶

Mutations in the BRAF, NRAS, and C‐KIT Genes of Patients Diagnosed with Melanoma in Colombia Population

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COLUMBIA: 40 Million People Exposed to Extreme Ultraviolet Radiation During the Whole Year

Cited by 7 publications

References 0 publications

Impact of a sun protection campaign in Medellín (Colombia)

Impact of a sun protection campaign in Medellín (Colombia)

Global Solar UV Index: Australian Measurements, Forecasts and Comparison with the UK¶

Mutations in the BRAF, NRAS, and C‐KIT Genes of Patients Diagnosed with Melanoma in Colombia Population

Contact Info

Product

Resources

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Global Solar UV Index: Australian Measurements, Forecasts and Comparison with the UK^¶