Co-managed protected areas globally provide economic and environmental benefits through an equal partnership with communities. However, the African context of natural resource co-management differs, necessitating further research. This paper examines if the co-management of iSimangaliso World Heritage Site’s natural resources in South Africa leads to sustainable use. Qualitative research was conducted via semi-structured interviews and random surveys were conducted with Khula Village residents. The results suggest partial success with challenges such as poaching, non-compliance, communication gaps and gender differentiation over land ownership. Some recommendations include transparency from the co-management committee with residents, education and empowerment programmes on co-management, and involvement of all residents, including non-landowners in co-management decisions for resource protection.