Combating human smuggling

Paunović, Nikola

doi:10.5937/bezbednost1703168p

Cited by 2 publications

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“…The experts mostly agree that depression is one of the most painful life experiences that person can deal with (1). Depression is a part of the large group of mood disorders, which is characterized by emotional disorder and by disturbances in judgment, cognition, volition, and instincts, with possible vegetative perturbations (2). Depressive patients experience feelings of unreasonable sadness, helplessness, hopelessness, loss of interest, and satisfaction, along with loss of energy and permanent fatigue (3).…”

Section: Review Paper Revijalni Rad Review Paper Revijalni Rad Reviewmentioning

confidence: 99%

Immunological Aspects of Depressive Disorder - The Review

Vojvodić

Mihajlović

Andonov

et al. 2024

Experimental and Applied Biomedical Research (EABR)

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Depression represents a mood disorder and is considered to be one of the most common mental disorders in general. World Health Organization estimates that depression will be the leading cause of disability-adjusted life years, until 2030. Depression is a complex heterogeneous disorder where immune system and its regulation play an important role. Innate and adaptive immunity mecha nisms are included, along with processes of immune activation and suppression. The expression of humoral factors of innate immunity, especially pro-inflammatory cytokines, is increased, whereas the intensity of cellular immune mechanisms, primarily T cells and NK cells, are impaired. The influence of pro-inflammatory cytokines on depression is reflected in their effect on certain enzymes and ensuing reduction of neurotransmitters serotonin and dopamine. They also affect the neuroendocrine function in central nervous system, resulting in increase of cortisol levels and inactivation of glucocorticoid receptors in the periphery, which leads to neurodegeneration and decrease in neurotransmitter production. Certain cytokines affect neuroplasticity through the decreasing of concentration of neurotrophic brain factor and induction of brain cell apoptosis. The results are often contradictory talking about mechanisms of adaptive immunity. On one hand, an increased activity of Tlymphocytes is observed, while on the other, there are evidence of spontaneous apoptosis and impaired function of these cells in depression. In addition, neuroprotective role of autoreactive and regulatory T cells in prevention of depression has also been demonstrated. The aim of this paper is to analyze the current knowledge on the role of immune mechanisms in the pathogenesis of depression.

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Section: Review Paper Revijalni Rad Review Paper Revijalni Rad Reviewmentioning

confidence: 99%

Immunological Aspects of Depressive Disorder - The Review

Vojvodić

Mihajlović

Andonov

et al. 2024

Experimental and Applied Biomedical Research (EABR)

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Prohibition of trafficking in human beings under the auspices of human rights

Šurlan¹

2021

Bezbednost, Beograd

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The following work is dedicated to the consideration of the prohibition of human trafficking from the aspect of human rights. The initial thesis is that human trafficking cannot be reduced only to the criminal law aspect, but that by standardizing this prohibition within the constitutions and international treaties in the field of human rights, this institute is positioned hierarchically at the highest level of the legal order. In the first part of the paper, the legal framework is examined, primarily international law and then constitutional law. The second part analyzes the decisions of the European Court of Human Rights and the Constitutional Court of the Republic of Serbia. The analysis of courts` decisions was used as a basis for the theoretical formulation of the most important aspects of the prohibition of trafficking in human beings as a category of human rights. Special emphasis was placed on the consideration of the positive obligations of the states undertaken by the ratification of international treaties in the field of human rights and the matter of the fight against human trafficking.

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Combating human smuggling

Cited by 2 publications

References 1 publication

Immunological Aspects of Depressive Disorder - The Review

Immunological Aspects of Depressive Disorder - The Review

Prohibition of trafficking in human beings under the auspices of human rights

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