Combination of 595-nm pulsed dye laser, long-pulsed 755-nm alexandrite laser, and microdermabrasion treatment for keratosis pilaris: retrospective analysis of 26 Korean patients

Lee, Sang Ju; Choi, Moon; Zheng, Zhenlong; Chung, Woo Sik; Kim, Young Koo; Cho, Sung Bin

doi:10.3109/14764172.2013.769276

Cited by 18 publications

(10 citation statements)

References 10 publications

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“…In most cases, reassurance and general skin care focusing on avoiding skin dryness are required. Emollients, keratolytic agents, topical steroids, chemical or mechanical peels, vitamin D3 analogues, and topical or systemic retinoids may be used [ 8 ]. Various laser or light-based therapies targeting different components of the lesion have been tried with variable success rate [ 4 , 5 , 10 , 11 ].…”

Section: Discussionmentioning

confidence: 99%

“…The proposed mechanism of long-pulsed 1064 nm Nd:YAG laser was to reduce the size of the affected hair follicles. According to a study by Lee et al, the combination of 595 nm pulsed dye laser, long-pulsed 755 nm alexandrite laser, and microdermabrasion to target 3 components of KP resulted in marked improvement of KP in 51.7% of patients [ 8 ]. Therefore, the most suitable choice for the treatment of KP mainly depends on the pronounced and problematic component.…”

Section: Discussionmentioning

confidence: 99%

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Fractional Carbon Dioxide Laser for Keratosis Pilaris: A Single-Blind, Randomized, Comparative Study

Vachiramon

Anusaksathien

Kanokrungsee

et al. 2016

BioMed Research International

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Objective. Keratosis pilaris (KP) is a common condition which can frequently be cosmetically disturbing. Topical treatments can be used with limited efficacy. The objective of this study is to evaluate the effectiveness and safety of fractional carbon dioxide (CO2) laser for the treatment of KP. Patients and Methods. A prospective, randomized, single-blinded, intraindividual comparative study was conducted on adult patients with KP. A single session of fractional CO2 laser was performed to one side of arm whereas the contralateral side served as control. Patients were scheduled for follow-up at 4 and 12 weeks after treatment. Clinical improvement was graded subjectively by blinded dermatologists. Patients rated treatment satisfaction at the end of the study. Results. Twenty patients completed the study. All patients stated that the laser treatment improved KP lesions. At 12-week follow-up, 30% of lesions on the laser-treated side had moderate to good improvement according to physicians' global assessment (p = 0.02). Keratotic papules and hyperpigmentation appeared to respond better than the erythematous component. Four patients with Fitzpatrick skin type V developed transient pigmentary alteration. Conclusions. Fractional CO2 laser treatment may be offered to patients with KP. Dark-skinned patients should be treated with special caution.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Fractional Carbon Dioxide Laser for Keratosis Pilaris: A Single-Blind, Randomized, Comparative Study

Vachiramon

Anusaksathien

Kanokrungsee

et al. 2016

BioMed Research International

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“…There are currently no laser therapies that can treat papules, erythema and pigmentation of keratosis pilaris at the same time. In addition, laser treatment has disadvantages of obvious pain, long recovery time, high cost, and long treatment cycles[ 4 ].…”

Section: Discussionmentioning

confidence: 99%

Clinical outcomes and 5-year follow-up results of keratosis pilaris treated by a high concentration of glycolic acid

Tian¹,

Li²,

Zhang³

et al. 2021

WJCC

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BACKGROUND Keratosis pilaris is a hereditary abnormal keratosis of the hair follicle orifice. Gray-brown keratotic plugs in the pores and dark red keratotic papules at the openings of hair follicles can be seen, which contain coiled hair and are often accompanied by perifollicular erythema and pigmentation. Glycolic acid can correct the abnormalities of hair follicular duct keratosis and eliminate excessive accumulation of keratinocytes. It also promotes skin metabolism and accelerates the melanin metabolism. The therapeutic effect is related to the glycolic acid concentration. AIM To evaluate the efficacy and safety of a high concentration of glycolic acid in the treatment of keratosis pilaris, and to observe the outcomes at 5-year of follow-up. METHODS Twenty-five participants were recruited and areas with typical keratosis pilaris were selected as testing sites. High concentrations of glycolic acid (50% or 70%) were applied to a circular area (d = 8 cm, S = 50 cm 2 ) and repeated four times, on days 0, 20, 40 and 60. Before each treatment and 20 d after the last treatment, on days 0, 20, 40, 60, and 80 and at a 5-year follow-up, The number of follicular keratotic papules were counted and the extent of perifollicular erythema and pigmentation was determined. At the same time, the participants provided subjective evaluations of treatment efficacy and safety. RESULTS Treatment effectiveness was indicated by the percentage of keratotic papules in the test site, on days 20, 40, 60 and 80, which were 8%, 12%, 36%, and 60%, respectively. Compared with day 0, each difference was significant ( P < 0.05). Compared with day 0, differences in melanin content (M) in the skin and skin lightness (L) on days 40, 60 and 80, the were statistically significant ( P < 0.05); skin hemoglobin content (E) on days 60 and 80 was statistically different as compared with before treatment ( P < 0.05). There were no significant differences in the number of keratotic papules, M, L, and E in 9 participants at the 5-year follow-up compared with before treatment ( P > 0.05%). CONCLUSION A high concentration of glycolic acid significantly improved skin roughness as well as follicular hyperpigmentation of patients with keratosis pilaris. The treatment was relatively safe, but there was no significant difference at the 5-year follow-up compared to before treatment.

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“…Dye lasers, due to capability to produce tunable laser lights in a wide range of wavelengths in addition to producing CW and pulsed lasers, have many applications in science [1][2][3][4][5][6], medicine [7][8][9][10][11], and industry [12][13][14]. A dye laser is generally pumped by a ash lamp or by the light of another laser.…”

Section: Introductionmentioning

confidence: 99%

Output power enhancement of Rh6G dye laser by colloidal gold nanoparticles

Moshaii

2016

Scientia Iranica

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Improvement of the e ciency of a Rhodamine 6G dye laser by adding proper concentrations of gold colloidal nanoparticles into the dye solution has experimentally been investigated. Gold colloidal nanoparticles, due to their strong plasmonic peak in the visible region, are expected to have a considerable interaction with Rhodamine 6G dye molecules with broad emission spectrum in the visible range. It is shown that with addition of enough low concentrations (less than 0.4 M/l) of gold nanoparticles to the dye solution, both the output power and the e ciency of the dye laser increase. The best improvement of the laser e ciency reaches 15%. Two amplifying mechanisms exist for e ciency improvement by the nanoparticles, which are resonant energy transfer from the plasmonic nanoparticles to the dye molecules and the high near eld around the nanoparticles. The results indicate that in low concentrations of gold nanoparticles, the amplifying mechanisms dominate the dissipating mechanism of scattering of the pumped light by the nanoparticles. This leads to the e ciency improvement by addition of the nanoparticles.

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Combination of 595-nm pulsed dye laser, long-pulsed 755-nm alexandrite laser, and microdermabrasion treatment for keratosis pilaris: retrospective analysis of 26 Korean patients

Cited by 18 publications

References 10 publications

Fractional Carbon Dioxide Laser for Keratosis Pilaris: A Single-Blind, Randomized, Comparative Study

Fractional Carbon Dioxide Laser for Keratosis Pilaris: A Single-Blind, Randomized, Comparative Study

Clinical outcomes and 5-year follow-up results of keratosis pilaris treated by a high concentration of glycolic acid

Output power enhancement of Rh6G dye laser by colloidal gold nanoparticles

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