Combination of dynapenia and abdominal obesity affects long-term physical performance trajectories in older adults: sex differences

Máximo, Roberta de Oliveira; Oliveira, Dayane Capra de; Ramírez, Paula Camila; Luiz, Mariane Marques; Souza, Aline Fernanda de; Delinocente, Maicon Luís Bicigo; Steptoe, Andrew; Oliveira, César de; Alexandre, Tiago da Silva

doi:10.1093/ajcn/nqac023

Cited by 19 publications

(15 citation statements)

References 45 publications

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“…Similar results have been described in the literature [ 11 , 62 ], demonstrating an association between worse strength and balance performance of lower limbs in older adults and increased weight and a higher percentage of body fat. In agreement with the literature, these associations are the result of the negative influence of adipose tissue on the reduction in neuromuscular function in the older adult population [ 63 , 64 ].…”

Section: Discussionsupporting

confidence: 88%

Older Women Who Practiced Physical Exercises before the COVID-19 Pandemic Present Metabolic Alterations and Worsened Functional Physical Capacity after One Year of Social Isolation

et al. 2022

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Background: Because the consequences of the lifestyle changes in older adults associated with the social isolation imposed in response to the COVID-19 pandemic are not fully understood, here, we investigated the effects of one year of social isolation imposed by COVID-19 on the metabolic parameters and functional physical capacity of older women who regularly practiced physical exercises before the pandemic. Methods: Systemic lipid and protein profiles, estimated creatinine clearance (ECC), and functional physical capacity (FPC) were assessed before (January-February 2020) and 12 months after social isolation in 30 older women (mean age 73.77 ± 6.22) who were engaged in a combined-exercise training program for at least 3 years before the COVID-19 pandemic. Results: In this group, we observed increased plasma levels of triglycerides and creatinine, an increase in the time necessary to perform gait speed and time-up-and-go tests, and reduced muscle strength assessed by the handgrip test and ECC post-COVID-19 pandemic relative to values recorded pre-pandemic. In addition, we observed significant correlations (both negative and positive) between anthropometric, some metabolic parameters, and physical tests. Conclusion: One year of interruption of physical exercise practice imposed in response to the COVID-19 pandemic significantly altered some systemic metabolic parameters and worsened ECC and FPC in older women.

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Section: Discussionsupporting

confidence: 88%

Older Women Who Practiced Physical Exercises before the COVID-19 Pandemic Present Metabolic Alterations and Worsened Functional Physical Capacity after One Year of Social Isolation

et al. 2022

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“…These physiological differences may lead to different responses to exercise. Men typically have more muscle mass and higher metabolic rate ( 48 ), therefore requiring higher intensity exercise to produce significant effects. And there are also differences in the types of comorbidities between males and females.…”

Section: Discussionmentioning

confidence: 99%

The effect of exercise intensity types on the self-rated health status of young-old comorbidities patients: a cross-sectional study in Guangdong, China

Li,

Dai,

Zhang

2023

Front. Public Health

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ObjectiveExplore the effect of different types of exercise intensity on the self-rated health status of young-old comorbid patients with cardiovascular disease and metabolic disease, as well as the differences in effect among different genders. Provide more references and suggestions for chronic disease management in older comorbidities patients based on the results of the study.MethodsA multi-stage stratified cluster random sampling method was used to select older (≥60 years old) comorbidities patients from communities in Guangdong Province as the survey subjects. Using the “Survey Questionnaire on the Current Status and Influencing Factors of older Comorbidities Patients,” face-to-face interviews were conducted with 1,300 old patients. Data from 965 young-old patients (aged 60–74) who simultaneously suffered from cardiovascular and metabolic diseases were selected. Unordered multifactor Logistic regression analysis was used to explore the association between the type of exercise intensity and self-rated health. Stratified analysis was performed based on gender.ResultsThe results of unordered multivariate logistic regression analysis showed that compared with young-old comorbidities patients with poor self-rated of health status, young-old comorbidities patients who underwent vigorous-intensity exercise were more likely to have better self-rated of health status (OR = 4.368, 95% CI: 2.491–7.661, p < 0.05). Stratified analysis based on gender showed that for young-old comorbidities male patients, those who engaged in vigorous-intensity exercise were more likely to have better self-rated of health status (OR = 2.924, 95% CI = 1.266–6.751, p < 0.05); for young-old comorbidities female patients, those who were encouraged by their family to exercise (OR = 2.460, 95% CI: 1.143–5.291, p < 0.05), participate in social activities (OR = 6.173, 95% CI: 2.285–16.678, p < 0.05), and engage in vigorous-intensity (OR = 4.232, 95% CI: 1.869–9.583, p < 0.05) or moderate-intensity exercise (OR = 4.555, 95% CI: 1.825–11.368, p < 0.05) were more likely to have better self-rated of health status.ConclusionIf the physical condition allows, vigorous-intensity exercise has a significant positive effect on the self-rated of health status of young-old comorbidities patients with cardiovascular disease and metabolic disease. Specifically, for young-old comorbidities male patients, those who engage in vigorous-intensity exercise are more likely to self-evaluate their health as good; for young-old comorbidities female patients, both vigorous-intensity and moderate-intensity exercise can improve their self-rated of health status.

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“…Therefore, we assessed the nonlinear mediation of sleep duration, BMI and GS. Besides, waist circumference or abdominal obesity was closely correlated to dynapenia [ 33 , 34 ], of which the mechanism appears to be different from that of BMI. Hence, we conducted another two nonlinear mediation analyses (Model 3) using waist circumference instead of BMI to examine the contribution of sleep duration to the dynapenia abdominal obesity phenotype.…”

Section: Methodsmentioning

confidence: 99%

Sleep duration affects the sequential change of body mass index and muscle strength: a contribution to dynapenic obesity

Zhang

Wang

et al. 2023

BMC Geriatr

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Background With aging, body mass index (BMI) increases and muscle strength declines, resulting in dynapenic obesity. It remains unknown whether and how sleep duration contributes to the sequence of BMI and muscle strength change in the progression of dynapenic obesity. Methods Data were derived from the first two waves of China Health and Retirement Longitudinal Study. Sleep duration was self-reported. BMI was calculated and grip strength (GS) was measured to reflect muscle strength. The effect of baseline sleep duration on the sequential change of BMI and GS was assessed using two mediation models considering the nonlinear associations between them. The moderating effect of metabolic disorder was also tested. Results Totally 4986 participants aged ≥ 50 years (50.8% females) with complete information on variables were included. Baseline BMI fully mediated the nonlinear association between sleep duration and follow-up GS change, but baseline GS did not mediate between sleep duration and follow-up BMI change for older men and women. Short sleep duration positively affected BMI-induced GS change (β = 0.038; 95%CI, 0.015–0.074), while this favorable effect became nonsignificant for moderate sleep duration (β = 0.008; 95% CI, -0.003–0.024) and turned negative with prolonged sleep duration (β = − 0.022; 95%CI, − 0.051 to − 0.003). This nonlinear mediation effect was more pronounced in older women who are relatively metabolically healthy at baseline. Conclusion For older adults in China, the influence of sleep duration on BMI-induced GS change but not the GS-induced BMI change suggested the contribution of sleep duration to the sequential course in the progression of dynapenic obesity. Sleep duration deviated either above or below normal range may confer adverse impact on GS through BMI. Strategies addressing sleep and obesity jointly to improve muscle function and delay the progression of dynapenic obesity are required.

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Combination of dynapenia and abdominal obesity affects long-term physical performance trajectories in older adults: sex differences

Cited by 19 publications

References 45 publications

Older Women Who Practiced Physical Exercises before the COVID-19 Pandemic Present Metabolic Alterations and Worsened Functional Physical Capacity after One Year of Social Isolation

Older Women Who Practiced Physical Exercises before the COVID-19 Pandemic Present Metabolic Alterations and Worsened Functional Physical Capacity after One Year of Social Isolation

The effect of exercise intensity types on the self-rated health status of young-old comorbidities patients: a cross-sectional study in Guangdong, China

Sleep duration affects the sequential change of body mass index and muscle strength: a contribution to dynapenic obesity

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