2010
DOI: 10.1016/j.jclinane.2009.02.020
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Combination of high-dose dexmedetomidine sedation and fascia iliaca compartment block for hip fracture surgery

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Cited by 10 publications
(8 citation statements)
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“…The maximum pCp of DEX (1.56 ng/mL) when the patient was turned to the lateral position was similar to that during an invasive procedure in a previous study [7], and the mean pCp of DEX (0.45 ng/mL) was less than the DEX concentration required for sedation in ICU patients [9]. Considering the scale of invasiveness, these values were thought to be reasonable.…”
Section: Discussionsupporting
confidence: 73%
“…The maximum pCp of DEX (1.56 ng/mL) when the patient was turned to the lateral position was similar to that during an invasive procedure in a previous study [7], and the mean pCp of DEX (0.45 ng/mL) was less than the DEX concentration required for sedation in ICU patients [9]. Considering the scale of invasiveness, these values were thought to be reasonable.…”
Section: Discussionsupporting
confidence: 73%
“…We appreciate the interest in our paper [1], as shown in the correspondence above. We believe, as Dr. Tyagi does, that "NSAIDs appear to represent no added significant risk for the development of spinal hematoma in patents having epidural or spinal anesthesia", as stated in the practice guidelines [2,3].…”
Section: Replymentioning
confidence: 82%
“…However, in true airway catastrophes, as presented in the case here, the level of analgesia and sedation achieved with the FDA recommended dosage may not be sufficient for the prescribed procedure. To this end, only a small handful of reports exist in the literature on the use of higher than FDA approved doses of dexmedetomidine in adults [19][20][21][22][23][24][25].…”
Section: Discussionmentioning
confidence: 99%