Combination of high-frequency ultrasound and virtual touch tissue imaging and quantification improve the diagnostic efficiency for mild carpal tunnel syndrome

Lai, Zhen-han; Yang, Sheng; Shen, Haolin; Luo, Yi; Cai, Xiaohan; Jiang, Wenting; Liao, Liping; Wu, Kunbin; Lv, Guorong

doi:10.1186/s12891-021-03982-7

Cited by 5 publications

(5 citation statements)

References 20 publications

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“…Moreover, recent advancements in imaging techniques, including high-resolution ultrasound and magnetic resonance imaging (MRI), have contributed to enhanced diagnostic accuracy ( 67 ). Ultrasound can visualize median nerve morphology and quantify its cross-sectional area, thus providing valuable anatomical information ( 68 ) while MRI offers the advantage of assessing soft tissue structures within the carpal tunnel, including ligaments and tendons ( 67 ). Table 4 provides an overview of the clinical manifestations and diagnostic indicators associated with Carpal Tunnel Syndrome (CTS).…”

Section: Resultsmentioning

confidence: 99%

“…Proactive workplace strategies, including ergonomic modifications, regular breaks for hand and wrist stretches, prove to be crucial in mitigating the risk of Carpal Tunnel Syndrome (CTS). Employing ergonomic principles, equipment modification, and task rotation, can help decrease the risk of CTS by reducing strain on the hands and wrists ( 68 ). Importantly, promoting awareness and providing education on proper ergonomics and hand hygiene practices can significantly contribute to prevention efforts in high-risk occupational settings ( 68 ).…”

Section: Resultsmentioning

confidence: 99%

“…Employing ergonomic principles, equipment modification, and task rotation, can help decrease the risk of CTS by reducing strain on the hands and wrists ( 68 ). Importantly, promoting awareness and providing education on proper ergonomics and hand hygiene practices can significantly contribute to prevention efforts in high-risk occupational settings ( 68 ).…”

Section: Resultsmentioning

confidence: 99%

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Occupational Carpal Tunnel Syndrome: a scoping review of causes, mechanisms, diagnosis, and intervention strategies

Rotaru-Zavaleanu,

Lungulescu,

Bunescu

et al. 2024

Front. Public Health

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Carpal Tunnel Syndrome (CTS) has traditionally been viewed as a specialized medical condition. However, its escalating prevalence among professionals across a multitude of industries has sparked substantial interest in recent years. This review aims to delve into CTS as an occupational disease, focusing on its epidemiological patterns, risk factors, symptoms, and management options, particularly emphasizing its relevance in professional environments. The complex interaction of anatomical, biomechanical, and pathophysiological factors that contribute to the development of CTS in different work settings underlines the critical role of ergonomic measures, prompt clinical identification, and tailored treatment plans in reducing its effects. Nevertheless, the challenges presented by existing research, including diverse methodologies and definitions, highlight the need for more unified protocols to thoroughly understand and tackle this issue. There’s a pressing demand for more in-depth research into the epidemiology of CTS, its injury mechanisms, and the potential role of targeted medicine. Moreover, recognizing CTS’s wider ramifications beyond personal health is essential. The economic burden associated with CTS-related healthcare costs, productivity losses, and compensation claims can significantly impact both businesses and the broader society. Therefore, initiatives aimed at preventing CTS through workplace interventions, education, and early intervention programs not only benefit the affected individuals but also contribute to the overall well-being of the workforce and economic productivity. By fostering a collaborative approach among healthcare professionals, employers, policymakers, and other stakeholders, we can strive towards creating safer and healthier work environments while effectively managing the challenges posed by CTS in occupational settings.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Occupational Carpal Tunnel Syndrome: a scoping review of causes, mechanisms, diagnosis, and intervention strategies

Rotaru-Zavaleanu,

Lungulescu,

Bunescu

et al. 2024

Front. Public Health

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“…The diagnostic tests evaluated and their weighted mean sensitivity and specificity are outlined in Tables 2 and 3. 16-128 Although studies utilizing “clinical diagnosis” as a reference standard were treated as a unified subset, many studies 16-128 were found to utilize different definitions of clinical diagnosis. An outline of the utilized definitions for “clinical diagnosis” is presented in Supplemental Digital Content 1.…”

Section: Resultsmentioning

confidence: 99%

The Impact of Reference Standard on Diagnostic Testing Characteristics for Carpal Tunnel Syndrome: A Systematic Review

Bennett

Sears

2023

Plastic and Reconstructive Surgery - Global Open

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Background: Lack of a reliable reference standard for carpal tunnel syndrome (CTS) diagnosis could impact the diagnostic test characteristics. This systematic review sought to evaluate differences in the accuracy of CTS diagnostic modalities based on the reference standard used. Methods: A systematic review was performed following PRISMA guidelines to investigate diagnostic modalities used in CTS. A literature search of Embase, PubMed, and Cochrane Reviews was conducted for the years of 2010–2021 for primary data, and 113 studies met final inclusion criteria. Studies were stratified based on the reference standard utilized and diagnostic modality assessed, and the weighted means of the sensitivities and specificities were calculated. Results: Thirty-five studies used clinical diagnosis alone as a reference standard, and 78 studies used electrodiagnostic study (EDS). The specificity for MRI and ultrasound (US) were substantially lower when EDS was used as the reference standard. MRI was the test most affected by the reference standard used, showing increased sensitivity when using EDS as the reference compared to clinical diagnosis (77.1% versus 60.9%) and decreased specificity (87.6% versus 99.2%). Regardless of the reference standard used, all tests had anticipated false-positive and/or false-negative rates of at least 10%. Conclusions: Testing characteristics vary greatly based on the choice of reference standard, with the sensitivity of MRI most affected. Regardless of reference standard used, EDS, US, and MRI each had false-positive and/or false-negative rates too great to be appropriate for use as a screening examination.

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“…It is a complement to conventional ultrasound in the assessment of neuropathy (18)(19)(20)(21). Studies have reported the significance of elastography in the assessment of CTS (22)(23)(24)(25). However, to the extent of our knowledge, there are few reports on the evaluation of pre-and post-operative changes in nerve stiffness in patients with CTS.…”

Section: Introductionmentioning

confidence: 99%

Ultrasound and elastography role in pre- and post-operative evaluation of median neuropathy in patients with carpal tunnel syndrome

Zhao

Xue

et al. 2022

Front. Neurol.

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IntroductionCarpal tunnel syndrome (CTS) is a common compression neuropathy of the median nerve in the wrist. Early diagnosis of CTS is essential for selecting treatment options and assessing prognosis. The current diagnosis of CTS is based on the patient's clinical symptoms, signs, and an electromyography (EMG) test. However, they have some limitations. Recently, ultrasound has been adopted as an adjunct diagnostic tool for electromyography (EMG). Ultrasound is a non-invasive and cost-effective technique. It provides a dynamic display of morphological changes in the median nerve and an assessment of CTS etiology such as tenosynovitis, mass compression, and tendon disease. This study aimed to investigate the value of conventional ultrasound and real-time shear wave elastography (SWE) in evaluation of median neuropathy in patients with carpal tunnel syndrome (CTS) before and after surgery.MethodsFirst, the Boston Carpal Tunnel Questionnaire (BCTQ) was administered to patients with CTS. All subjects were measured at three levels: the distal 1/3 of the forearm, the carpal tunnel inlet, and the distal carpal tunnel using conventional ultrasound and SWE. Median nerve parameters were examined in patients with CTS 1 week after surgery.ResultsThe cross-sectional area (CSA) and stiffness of the median nerve at the carpal tunnel inlet and distal carpal tunnel were significantly higher in patients with CTS than in healthy controls (p < 0.001). The CSA and stiffness of the median nerve at the carpal tunnel inlet were statistically significantly significantly between pre- and postoperative patients with CTS (p < 0.001). The CSA and stiffness of the nerve in patients with CTS had a positive correlation with electrophysiology severity.Conclusions and discussionConventional ultrasound and elastography are valuable in the diagnosis of CTS and are useful in the clinical assessment of patient's nerve recovery after operation.

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Combination of high-frequency ultrasound and virtual touch tissue imaging and quantification improve the diagnostic efficiency for mild carpal tunnel syndrome

Cited by 5 publications

References 20 publications

Occupational Carpal Tunnel Syndrome: a scoping review of causes, mechanisms, diagnosis, and intervention strategies

Occupational Carpal Tunnel Syndrome: a scoping review of causes, mechanisms, diagnosis, and intervention strategies

The Impact of Reference Standard on Diagnostic Testing Characteristics for Carpal Tunnel Syndrome: A Systematic Review

Ultrasound and elastography role in pre- and post-operative evaluation of median neuropathy in patients with carpal tunnel syndrome

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