Combination of microneedling and 10% trichloroacetic acid peels in the management of infraorbital dark circles

Kontochristopoulos, George; Kouris, Anargyros; Platsidaki, Eftychia; Markantoni, Vasiliki; Gerodimou, Maria; Antoniou, Christina

doi:10.3109/14764172.2016.1157363

Cited by 40 publications

(33 citation statements)

References 11 publications

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“…The effects were assessed on the basis of patient and physician global assessment and photo‐documentation. Almost all patients observed significant aesthetic improvement (Kontochristopoulos et al, ).…”

Section: Main Indications For the Application Of Microneedlingmentioning

confidence: 99%

Is skin microneedling a good alternative method of various skin defects removal

Zduńska

Kołodziejczak

Rotsztejn

2018

Dermatologic Therapy

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Skin microneedling accelerates the process of skin regeneration through the creation of numerous microinjuries which emerge when skin is deeply punctured with very thin needles. The whole procedure evokes various reactions which can be divided into three major phases: inflammation, proliferation, and remodeling. It activates platelet growth factors which are responsible for the stimulation of fibroblasts to produce collagen and elastin. Moreover, skin breakdown enhances penetration of active ingredients. Treatment can be performed with the use of different devices, all equipped with needles of various lengths. Due to the fact that skin microneedling stimulates the synthesis of significant rebuilding and structural skin elements (collagen, elastin, proteoglycan), it is used in the treatment of many skin defects of different etiologies (e.g., photoaging, wrinkles, loss of elasticity, hypo‐ or hypertrophic scars, pigmentation changes, infraorbital dark circles, teleangiectasia, stretch marks, cellulite, alopecia, and vitiligo). In order to accelerate postsurgical regeneration and/or to enhance effects, microneedling is combined with the application of UV light (photodynamic therapy with ALA), LED light, platelet‐rich plasma, chemical peels, stem cells, retinoids and other pharmaceuticals, and vitamins. High effectiveness, limited number of side effects, and short recovery time, make skin microneedling a popular cosmetic, and medical treatment.

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Section: Main Indications For the Application Of Microneedlingmentioning

confidence: 99%

Is skin microneedling a good alternative method of various skin defects removal

Zduńska

Kołodziejczak

Rotsztejn

2018

Dermatologic Therapy

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“…Chemical peeling is used to treat a diversity of facial pigmentary conditions as the peeling agents eliminate melanin from the stratum corneum and epidermis . A previous report has documented significant improvement when 10% trichloroacetic acid (TCA) was applied in patients with dark circles …”

Section: Introductionmentioning

confidence: 92%

“…10 A previous report has documented significant improvement when 10% trichloroacetic acid (TCA) was applied in patients with dark circles. 11 Comparative studies are highly recommended to determine the efficacy of PRP and chemical peeling in POH. To the best of our knowledge, this is the first study designed to compare the therapeutic effectiveness and tolerability of using PRP and chemical peeling in the treatment of POH.…”

mentioning

confidence: 99%

Efficacy and tolerability of using platelet‐rich plasma versus chemical peeling in periorbital hyperpigmentation

Ellabban¹,

Eyada

Nada

et al. 2019

J of Cosmetic Dermatology

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Background Various therapeutic modalities for periorbital hyperpigmentation (POH) have been proposed. Objective This study was designed to compare the efficacy and tolerability of autologous platelet‐rich plasma (PRP) and chemical peeling in POH. Subjects and methods Forty‐two patients were enrolled in this study and randomly subdivided into two groups. Group A patients were assigned to receive four sessions of chemical peeling using trichloroacetic acid and lactic acid, while group B was assigned to patients who received four sessions of PRP injection with 2 weeks of intervals. Patients were assessed by digital photographs. The degree of improvement included four degrees from poor to excellent, and side effects were reported. Results Females constituted 38 out of 42 patients (mean age, 28.14 ± 3.47 years). There was a significant improvement in favor of chemical peeling over PRP. Good improvement occurred in 47.6% in the group A versus 4.8% in group B (P < 0.001). None of the PRP group had excellent improvement, while 38% of chemical peeling group did. Most of group A patients reported very pleased (47.6%) to excellent (38%) degree, in contrast to group B where 52.5% were just pleased (P < 0.001). Some of group A patients experienced itching (14.3%) and redness (14.3%), while in group B, they experienced pain (23.8%) and edema (14.3%) with nonsignificant difference between both groups (P = 0.07). Conclusions Both PRP and chemical peeling are effective for treatment of POH; however, chemical peeling is much more effective, tolerable, and satisfying procedure than PRP.

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“…We have previously used this assessment scale in published research (Kontochristopoulos et al, 2016).…”

mentioning

confidence: 99%

Topical glycopyrronium in Darier's disease

Stravodimou

Markantoni

Platsidaki

et al. 2019

Dermatologic Therapy

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Combination of microneedling and 10% trichloroacetic acid peels in the management of infraorbital dark circles

Abstract: Microneedling and 10% TCA constitute an innovative combination treatment for DC with encouraging results and minor side effects.

Cited by 40 publications

References 11 publications

Is skin microneedling a good alternative method of various skin defects removal

Is skin microneedling a good alternative method of various skin defects removal

Efficacy and tolerability of using platelet‐rich plasma versus chemical peeling in periorbital hyperpigmentation

Topical glycopyrronium in Darier's disease

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