Combination of non-invasive and semi-invasive tests for diagnosis of minimal to mild endometriosis

Sharkwy, Ibrahim Abd Elgafor El

doi:10.1007/s00404-013-2822-z

Cited by 18 publications

(6 citation statements)

References 19 publications

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“…Eight studies were at low risk of bias in the 'reference standard' domain (Cho 2012;el Sharkwy 2013;Gagné 2003;Guerriero 1996a;Guerriero 1996b; Marasinghe 2014; Paiva 2014; Yun 2014), three studies were classified as unclear risk and no studies demonstrated a high risk. An unclear risk of bias was assigned if there was not enough information to determine how likely the reference standard was to have correctly classified the target condition.…”

Section: Librarymentioning

confidence: 99%

Combination of the non-invasive tests for the diagnosis of endometriosis

Nisenblat

Prentice

Bossuyt

et al. 2016

Cochrane Database of Systematic Reviews

148

152

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Section: Librarymentioning

confidence: 99%

Combination of the non-invasive tests for the diagnosis of endometriosis

Nisenblat

Prentice

Bossuyt

et al. 2016

Cochrane Database of Systematic Reviews

148

152

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“…Biomarkers can be also taken into consideration in the endometriosis diagnosis but none of them have adequate reliability for clinical use. Therefore, laparoscopy remains the gold standard for definitive diagnosis of endometriosis [ 24 ]. The treatment options for endometriosis include hormonal therapies, to achieve a hypo-oestrogenic status (oral contraceptives, progestins, danazol, GnRH agonists), pain-relieving agents (nonsteroidal anti-inflammatories, opioids) or surgical removal of endometriotic implants [ 25 , 26 ].…”

Section: Introductionmentioning

confidence: 99%

The Burden of Endometriosis on Women’s Lifespan: A Narrative Overview on Quality of Life and Psychosocial Wellbeing

Corte

Filippo

Gabrielli

et al. 2020

IJERPH

182

105

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Endometriosis is a chronic, inflammatory disease affecting more than 170 million women worldwide and up to 10% of women of reproductive age. As a consequence of inflammatory reaction and infiltration of anatomic structures, endometriosis can cause “pain symptoms” including dysmenorrhea, dyspareunia, dyschezia, dysuria, and chronic pelvic pain. In this review, we summarized the impact of endometriosis on quality of life in all its aspects including sexual life, work, and social relationships. The data research was conducted using web-based search engines and/or various electronic research databases querying for all articles related to endometriosis and quality of life from the inception of the database up to February 2020. Endometriosis has not only physical but also psychological effects, causing depression, anxiety, and compromising social relationships. Furthermore, endometriosis negatively impacts sexual life and social relationships. At last, the economic burden of endometriosis should not be underestimated, both individually and for the community, as this pathology leads to a loss of productivity at work and large use of health resources. Thus, endometriosis-related symptoms control women’s lives compromising the quality of life in all aspects. In this review, we summarized the impact of endometriosis on various aspects of women’s lives.

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“…For these reasons, development of sensitive and specific non-invasive tests for endometriosis is a priority for investigators [169]. Many DNA-based non-invasive diagnostics methods are used in the clinical practice in obstetrics and gynecology [170].…”

Section: Introductionmentioning

confidence: 99%

Molecular aspects of development and regulation of endometriosis

Aznaurova

Жуматаев

Roberts

et al. 2014

Reprod Biol Endocrinol

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Endometriosis is a common and painful condition affecting women of reproductive age. While the underlying pathophysiology is still largely unknown, much advancement has been made in understanding the progression of the disease. In recent years, a great deal of research has focused on non-invasive diagnostic tools, such as biomarkers, as well as identification of potential therapeutic targets. In this article, we will review the etiology and cellular mechanisms associated with endometriosis as well as the current diagnostic tools and therapies. We will then discuss the more recent genomic and proteomic studies and how these data may guide development of novel diagnostics and therapeutics. The current diagnostic tools are invasive and current therapies primarily treat the symptoms of endometriosis. Optimally, the advancement of “-omic” data will facilitate the development of non-invasive diagnostic biomarkers as well as therapeutics that target the pathophysiology of the disease and halt, or even reverse, progression. However, the amount of data generated by these types of studies is vast and bioinformatics analysis, such as we present here, will be critical to identification of appropriate targets for further study.

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Combination of non-invasive and semi-invasive tests for diagnosis of minimal to mild endometriosis

Abstract: Combination of both serum IL-6 and presence of nerve fibres in the endometrium is more reliable method for diagnosis of MM endometriosis than in single test.

Cited by 18 publications

References 19 publications

Combination of the non-invasive tests for the diagnosis of endometriosis

Combination of the non-invasive tests for the diagnosis of endometriosis

The Burden of Endometriosis on Women’s Lifespan: A Narrative Overview on Quality of Life and Psychosocial Wellbeing

Molecular aspects of development and regulation of endometriosis

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