Abstract:In young adults 20%-47% cases of stroke is due to cardiac embolism. Cardiac Myxoma is an infrequent cause of embolic stroke in young. We are reporting a case of a ischemic stroke in a young adult of 34 years with a history of recreational drug use who was eventually diagnosed with Left Ventricular Apical Myxoma, Systemic Lupus Erythematous (SLE), Lupus Nephritis, Secondary Anti phospholipid Syndrome, Hyper homocysteinemia, and Dyslipidemia.