Combination of strontium chloride and photobiomodulation in the control of tooth sensitivity post-bleaching: A split-mouth randomized clinical trial

Abstract

Objective This split-mouth randomized controlled clinical trial assessed the effect of 10% strontium chloride in combination with photobiomodulation (PBM) for the control of tooth sensitivity (TS) post-bleaching. Methods The upper/lower, right and left quadrants of fifty volunteers were randomized and allocated to four groups (n = 25): PLACEBO—placebo gel + simulation of PBM; Placebo + PBM; STRONTIUM—10% strontium chloride + simulation of PBM; and PBM + STRONTIUM—10% strontium chloride + PBM. All groups received tooth bleaching treatment with 35% hydrogen peroxide. For the PBM treatment, the laser tip was positioned in the apical and cervical regions of the teeth bleached in the respective hemi-arch. The laser system was operated in continuous mode, using 1.7 J of energy. A dose of 60 J/cm2 was applied to each point for 16 seconds under 808 nm near-infrared light (100mW of power), with a point area of 0.028 cm2. TS was assessed during a 21-day follow-up, using the modified visual analogue scale. Results In the intragroup assessment, the Friedman test indicated that PBM + STRONTIUM promoted the greatest reduction in TS after the second week of treatment (p ≤ 0.05). The Wilcoxon-Mann-Whitney test indicated that the groups Placebo + PBM, STRONTIUM, and STRONTIUM + PBM did not differ statistically (p ≥ 0.05) in the first and third weeks of treatment The group PLACEBO exhibited the greatest TS in the first three days after each bleaching session. Conclusion The combination of 10% strontium chloride with PBM was effective in reducing post-bleaching TS; however, the combination of 10% strontium chloride with PBM was effective in reducing post-bleaching TS; however, it did not differ from the individual use of Placebo + PBM or STRONTIUM groups assessed after 21 days of follow-up.

The effect of photobiomodulation therapy associated with casein phosphopeptide‐amorphous calcium phosphate fluoride paste on the treatment of posthome whitening tooth sensitivity and color change: A randomized clinical trial

“…Nevertheless, the study revealed the rather promising effect of potassium nitrate or PBMT alone. Similar results were found by Pompeu et al ( 2021 ) when combining 10% strontium chloride with PBMT, which was effective in reducing post‐whitening TS, but not significantly different from using PBMT or strontium chloride alone. In this study, combining PBMT with CPP‐ACPF proved more effective in reducing pain in the second and third weeks of evaluation than using PBMT or CPP‐ACPF alone.…”

“…According to Sharma et al ( 2005 ) the CIEDE2000 formula is most compatible with visual perception and acceptance of color change because shade measurements are fitted to three parameters: lightness, hue and chroma. Although, the advantages of CIEDE2000, the CIELab color space system remains commonly used to measure changes in shade during TW clinical trials (de Paula et al, 2019 ; Pompeu et al, 2021 ). Therefore, using the CIELab color space system enables to compare data between different clinical trials and may help to improve the scientific evidence.…”

“…Consequently, H02 cannot be rejected in this study. The clinical trials that have evaluated PBMT or CPP‐ACPF alone have also concluded that these desensitizing treatments did not interfere with the effectiveness of TW (Alencar et al, 2018 ; Alexandrino et al, 2017 ; de Paula et al, 2019 ; Gama Cunha et al, 2012 ; Pompeu et al, 2021 ). In this study, shade was determined in canines because they are the darkest teeth naturally, which allows more sensitive color change evaluation (Wetter et al, 2009 ).…”

Evaluation of the ozonated sunflower oil application on reducing sensitivity after at-home bleaching

“…Its mechanism of action is based on the production capacity of free radicals by hydrogen peroxide (H2O2) that oxidizes the pigmented organic molecules of the tooth structure. Thus, its low molecular weight causes its diffusion in the interprismatic spaces of enamel to occur rapidly, reaching the pulp chamber and producing oxidative stress in the cells present there that release in ammatory mediators with consequent sensitization of noceptors, causing the most common adverse effect in bleaching treatments, dentin hypersensitivity 12 .…”

Dentin Hypersensitivity: Etiology, Diagnosis and Contemporary Therapeutic Approaches—A Review in Literature

“…Strontium chloride (SrCl 2 ), usually at a concentration of 10%, operates in a manner reminiscent of calcium within the human body [93]. It has the potential to act as a substitute for apatite biomineralization, as has been described in previous reports [94].…”