Combination of Xylanase and Bacillus Direct-fed Microbials, as an Alternative to Antibiotic Growth Promoters, Improves Live Performance and Gut Health in Subclinical Challenged Broilers

Nusairat, Basheer; McNaughton, James; Tyus, James; Wang, Jeng-Jie

doi:10.3923/ijps.2018.362.366

Cited by 11 publications

(12 citation statements)

References 8 publications

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“…Supplementation of xylanase reduced ( P = 0.0001) 42-day lesion scores by 13, 14.7, and 24% for NC + 10, NC + 12.5, and NC + 15 compared with NC, respectively. These results are in agreement with the findings of Nusairat et al ( 29 ) that xylanase at 15 XU/g of feed reduced lesion score at 21 and 42 days of age. There was no imposed C. perfringens challenge implemented in this trial; however, birds were raised on used litter, which could potentially contain Clostridia and other pathogens.…”

Section: Resultssupporting

confidence: 93%

The Effect of a Modified GH11 Xylanase on Live Performance, Gut Health, and Clostridium perfringens Excretion of Broilers Fed Corn-Soy Diets

Nusairat

Wang²

2021

Front. Vet. Sci.

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Xylanase enzymes and other feed additives are being used more commonly in poultry feed to reduce feed cost, improve performance, and maintain gut health. Five corn-soy-based dietary treatments were designed to compare the effect of different inclusion levels of high-efficiency GH11 xylanase on live performance, gut lesions, and Clostridium perfringens excretion in littler samples of broiler chickens. Diets were the standard diet (positive control; PC); a diet of reduced energy by 130 kcal/kg diet (negative control; NC); NC with xylanase at 10 XU/g of feed (NC + 10); NC with xylanase at 12.5 XU/g of feed (NC + 12.5); NC with xylanase at 15 XU/g of feed (NC + 15). Data were analyzed with one-way ANOVA. At 42 d, birds fed NC + 12.5 and NC + 15 were heavier (P < 0.05) than NC and comparable improvement to birds fed PC. Significant Improvement in FCR (P = 0.0001) was observed from 1 to 42 d for NC + 12.5 and NC + 15 compared with NC. Supplementation of xylanase reduced (P < 0.005) 21 d intestinal lesion score at 21 d with further improvement (P < 0.0001) at 42 d. NC + 15 reduced lesion scores by 24% compared with NC. Xylanase supplementations reduced litter C. perfringens cell forming unit per gram (CFU/g) compared with NC with the highest reduction of NC + 15 treatment by ~27%. In conclusion, xylanase can be included in reduced-energy diets up to 15 XU/g of feed to improve live performance, energy digestibility, and reduce intestinal lesion scores in broilers.

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Section: Resultssupporting

confidence: 93%

The Effect of a Modified GH11 Xylanase on Live Performance, Gut Health, and Clostridium perfringens Excretion of Broilers Fed Corn-Soy Diets

Nusairat

Wang²

2021

Front. Vet. Sci.

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“…However, their combined action did not yield greater gains than the diets supplemented with the individual additives, thus indicating the absence of an additive effect. This finding contrasts with the results reported by Nusairat et al (2018), who studied the combined use of xylanase and Bacillus as an alternative to growth promoters and concluded that co-supplementation significantly improved feed conversion and intestinal injury score.…”

Section: Discussioncontrasting

confidence: 99%

Effects of xylanase and probiotic supplementation on broiler chicken diets

Machado

Cruz

Brasil

et al. 2020

Revista Brasileira De Zootecnia

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The objective of the present study was to evaluate the effects of xylanase and probiotic supplementation on the performance, carcass characteristics, intestinal pH, intestinal viscosity, and ileal microbiota of broiler chickens fed diets containing wheat bran. The study animals were kept in metal cages, and the study was performed using a completely randomized design, with four treatments, six birds per treatment, and six replicates. The four treatments included a control group, a probiotic-supplemented group, a xylanase-supplemented group, and a group that received both xylanase and probiotic supplementation. The diets of all four groups contained wheat bran (50 and 30 g/kg for the starter and grower phases, respectively) and phytase, and at 10 d after hatching, the experimental birds were challenged orally with Eimeria sp commercial vaccine. During the initial phase, supplementation with xylanase, probiotics, or their combination yielded greater weight gains than the control diet; however, considering the period from 10-35 d, the chickens receiving xylanase + probiotic and the diet without the additives showed lower weight gain (2.746 and 2.600 kg, respectively). All the supplemented diets reduced cecum viscosity, and supplementation with probiotic showed a significantly lower pH (6.11). The ileal microbiota was also influenced by xylanase and probiotic supplementation, modulating the frequencies of the genera Lactobacillus and Clostridium. The positive effects of supplementation with xylanase or probiotics alone were similar to those of co-supplementation, and no associative effect was observed.

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“…On the other hand, EnzaPro supplementation improved body weight and body weight gain without significantly affecting feed intake, which supports the finding that body weight improvements were not driven by feed intake, but rather by supplementation. These findings are consistent with the previously published effect of EnzaPro supplementation on the performance of broilers [ 18 , 34 ]. These studies also reflected on the improved ( p < 0.05) FCR from 1 to 42 d, which is consistent with the current trial, with two points of FCR improvement due to EnzaPro supplementation.…”

Section: Discussionsupporting

confidence: 93%

Live Performance and Microbial Load Modulation of Broilers Fed a Direct-Fed Microbials (DFM) and Xylanase Combination

Nusairat

Odetallah²,

Wang³

2022

Veterinary Sciences

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The animal industry, which focuses on producing protein for human consumption, is continuously seeking solutions that can enhance both animal performance and health at a low cost. Several feed additives are currently being used to improve the nutritive value of feed as well as replacing the subtherapeutic levels of antibiotic growth promoters (AGP). This study was designed to investigate the effect of a feed additive that is a blend of multi-strain Bacillus spp. probiotics and a xylanase in a 2 × 2 factorial dietary treatments design, testing two levels of the feed additive blend (0 and 100 g/MT) and two cereal grain types (corn and wheat) on live performance, gut lesions, environmental Clostridium perfringens load, and pathogen load in the digesta of broiler chickens (E. tenella, total aerobic count cells (APC), E. coli, and C. perfringens). Day-old chicks were randomly placed in 10 replicate pens per treatment with 52 birds per replicate and grown to 42 d of age. Data were analyzed by two-way ANOVA. At 42 d, birds fed EnzaPro were heavier (p < 0.0004) than unsupplemented birds. An improvement in FCR (p = 0.03) was observed from 1 to 42 d by approximately two points in both corn- and wheat-based diets supplemented with EnzaPro. In wheat-based diets, supplementing EnzaPro reduced (p < 0.0001) a 21 d lesion score of intestines with a further reduction (p < 0.02) at 42 d. EnzaPro reduced (p < 0.03) litter moisture by approximately 1% compared to non-supplemented EnzaPro in both corn- and wheat-based diets. Pathogen load in digesta (C. perfringens, E. tenella, APC, and E. coli) was reduced (p < 0.0002) when EnzaPro was supplemented in diets. It can be concluded that EnzaPro (a blend of DFM Bacillus spp (1 × 105 CFU/g feed) and xylanase (10 XU/g feed)) may be used in both corn- and wheat-based diets to improve the performance and gut health of broilers.

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Combination of Xylanase and Bacillus Direct-fed Microbials, as an Alternative to Antibiotic Growth Promoters, Improves Live Performance and Gut Health in Subclinical Challenged Broilers

Cited by 11 publications

References 8 publications

The Effect of a Modified GH11 Xylanase on Live Performance, Gut Health, and Clostridium perfringens Excretion of Broilers Fed Corn-Soy Diets

The Effect of a Modified GH11 Xylanase on Live Performance, Gut Health, and Clostridium perfringens Excretion of Broilers Fed Corn-Soy Diets

Effects of xylanase and probiotic supplementation on broiler chicken diets

Live Performance and Microbial Load Modulation of Broilers Fed a Direct-Fed Microbials (DFM) and Xylanase Combination

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