Combination Therapeutic Approach for Asthma and Allergic Rhinitis

Chauhan, Bhupendrasinh F; Patel, Madhabhai M.; Padh, Harish; Nivsarkar, Manish

doi:10.2174/157488408785747700

Cited by 5 publications

(2 citation statements)

References 115 publications

(92 reference statements)

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“…In agreement with previous report [58], conservative treatment in this study was done using mono therapy with steroid nasal spray fluticasone which does not result in complete relief of symptoms and so prolongs the hospital visit and affect compliance with long term use.…”

Section: Discussionsupporting

confidence: 89%

Allergic rhinitis and its associated co-morbidities at Bugando Medical Centre in Northwestern Tanzania; A prospective review of 190 cases

Said

Mchembe

Chalya

et al. 2012

BMC Ear Nose Throat Disord

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BackgroundAllergic rhinitis is one of the commonest atopic diseases which contribute to significant morbidity world wide while its epidemiology in Tanzania remains sparse. There was paucity of information regarding allergic rhinitis in our setting; therefore it was important to conduct this study to describe our experience on allergic rhinitis, associated co-morbidities and treatment outcome in patients attending Bugando Medical Centre.MethodsThis was descriptive cross-sectional study involving all patients with a clinical diagnosis of allergic rhinitis at Bugando Medical Centre over a three-month period between June 2011 and August 2011. Data was collected using a pre-tested coded questionnaire and analyzed using SPSS statistical computer software version 17.0.ResultsA total of 190 patients were studied giving the prevalence of allergic rhinitis 14.7%. The median age of the patients was 8.5 years. The male to female ratio was 1:1. Adenoid hypertrophy, tonsillitis, hypertrophy of inferior turbinate, nasal polyps, otitis media and sinusitis were the most common co-morbidities affecting 92.6% of cases and were the major reason for attending hospital services. Sleep disturbance was common in children with adenoids hypertrophy (χ2 = 28.691, P = 0.000). Allergic conjunctivitis was found in 51.9%. The most common identified triggers were dust, strong perfume odors and cold weather (P < 0.05). Strong perfume odors affect female than males (χ2 = 4.583, P = 0.032). In this study family history of allergic rhinitis was not a significant risk factor (P =0.423). The majority of patients (68.8%) were treated surgically for allergic rhinitis co morbidities. Post operative complication and mortality rates were 2.9% and 1.6% respectively. The overall median duration of hospital stay of in-patients was 3 days (2 – 28 days). Most patients (98.4%) had satisfactory results at discharge.ConclusionThe study shows that allergic rhinitis is common in our settings representing 14.7% of all otorhinolaryngology and commonly affecting children and adolescent. Sufferers seek medical services due to co-morbidities of which combination of surgical and medical treatment was needed. High index of suspicions in diagnosing allergic rhinitis and early treatment is recommended.

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Section: Discussionsupporting

confidence: 89%

Allergic rhinitis and its associated co-morbidities at Bugando Medical Centre in Northwestern Tanzania; A prospective review of 190 cases

Said

Mchembe

Chalya

et al. 2012

BMC Ear Nose Throat Disord

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show abstract

“…Apesar da disponibilidade de várias terapias nos últimos anos (GALLI et al, 2008;CHAUHAN et al, 2008;MELTZER, 2011;SEIBERLING et al, 2012;YANAI et al, 2012;MELTZER, 2013;BENEDÉ et al, 2016;MEHTA et al, 2016), o controle dos sintomas alérgicos, para muitos pacientes, permanece em níveis subótimos.…”

Section: Tratamento Das Doenças Alérgicasunclassified

Síntese de derivados da mangiferina, avaliação do potencial antialérgico e efeitos na membrana biológica

Bertoz¹

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Intranasal administration of a combination of choline chloride, vitamin C, and selenium attenuates the allergic effect in a mouse model of airway disease

Bansal¹,

Saw²,

Govindaraj³

et al. 2014

Free Radical Biology and Medicine

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Combination Therapeutic Approach for Asthma and Allergic Rhinitis

Abstract: From the available scientific data from clinical trials it can be concluded that combination therapeutic approach may be a viable option for the treatment of asthma and allergic rhinitis.

Cited by 5 publications

References 115 publications

Allergic rhinitis and its associated co-morbidities at Bugando Medical Centre in Northwestern Tanzania; A prospective review of 190 cases

Allergic rhinitis and its associated co-morbidities at Bugando Medical Centre in Northwestern Tanzania; A prospective review of 190 cases

Síntese de derivados da mangiferina, avaliação do potencial antialérgico e efeitos na membrana biológica

Intranasal administration of a combination of choline chloride, vitamin C, and selenium attenuates the allergic effect in a mouse model of airway disease

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