Combination Therapies with a Proton Pump Inhibitor for Helicobacter pylori-Infected Gastric Ulcer Patients

Clarithromycin Dual Therapy Regimens for Eradication ofHelicobacter pylori: A Review

“…Limited data are available with other dual therapy combinations including clarithromycin, with ten reports of studies with lansoprazole [72–81] and four of studies with ranitidine [82–85]. These are summarized in Tables 3 and 4, respectively.…”

“…Ten reports including 16 treatment arms of lansoprazole plus clarithromycin have been described [72–81]. The pooled reported eradication rate is 62% ( n = 200/322), range 46–73% [72,73,75–79].…”

Emerging Therapies for the Treatment of Helicobacter pylori Infections

“…However, the combination of lansoprazole, plaunotol, and clarithromycin was shown to produce an eradication rate of only 46% (11/24), 96 which is similar to that reported for plaunotol, amoxicillin, and lansoprazole. 97 The overall incidence of reported adverse effects was low for triple regimens that contained plaunotol.…”

Treatment of H. pylori Infection: A Review

“…It has been succesfully tested in H. pylori eradication, firstly in monkeys [142]. Then it has been studied in association with lansoprazole and amoxicillin or nitroimidazole: results have shown an increased eradication rate when compared to a dual therapy [143][144][145][146]. Only one study was performed in comparison to a triple therapy: ecabet sodium based triple therapy reached an eradication rate similar to a lansoprazole based one (85% vs 85%) [147].…”