Combination Treatments of 755 nm Alexandrite Laser with 1,064 nm Nd:YAG Laser Toning for Café Au Lait Macule

Yoo, Kwang Ho; Bang, Dongsik; Kim, Hee Su; Joe, and Brandon H.

doi:10.25289/ml.2015.4.2.78

Cited by 3 publications

(2 citation statements)

References 7 publications

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“…7 Since then, several studies have reported the good effect and low recurrence rate (0%−24.1%) of the LFQS 1064-nm laser in the treatment of CALMs. [8][9][10][11][12][13] However, the most popular lasers used currently are the QS 755-nm laser and QS 532-nm laser. Our study confirmed these had similar efficacy.…”

Section: Introductionmentioning

confidence: 99%

“…In 2009, Kim first used LFQS 1064‐nm laser to successfully treat a patient with CALM that could not be effectively removed by previous laser, grinding, and bleaching treatments 7 . Since then, several studies have reported the good effect and low recurrence rate (0%−24.1%) of the LFQS 1064‐nm laser in the treatment of CALMs 8–13 . However, the most popular lasers used currently are the QS 755‐nm laser and QS 532‐nm laser.…”

Section: Introductionmentioning

confidence: 99%

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Comparison of the safety and efficacy of low fluence Q‐switched 1064‐nm and conventional Q‐Switched 755‐nm lasers in the treatment of café‐au‐lait macules: A prospective self‐controlled trial

et al. 2022

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Background Conventional high fluence Q‐switched (HFQS) Alexandrite 755‐nm are widely used in clinical café‐au‐lait macules (CALMs) treatment. There have been recent concerns regarding the efficacy and safety of low fluence Q‐switched (LFQS) Nd: YAG 1064‐nm lasers. Objective To evaluate the efficacy and safety of the conventional HFQS and LFQS laser in the treatment of CALMs. Methods Within 3 months, 20 patients underwent prospective self‐controlled split‐lesion treatments with HFQS once or twice depending on the recovery rate, and with LFQS six times biweekly. Then the more effective laser was selected for continued treatments. Efficacy outcomes were evaluated by a visual analog scale (VAS) biweekly during the comparative trail. Recovery process, side effects and recurrence were recorded during the trial and follow‐up visit. Patient and physician preferences for laser selection were also recorded. Results The average VAS scores of areas treated with HFQS and LFQS were 2.92 ± 0.86 and 2.93 ± 1.13, respectively (p > 0.05). The most significant efficacy change of LFQS was after the fourth laser treatment (VAS score: 1.82−2.37, p < 0.001). 11 lesions treated with LFQS and 7 with HFQS achieved an optimal treatment response (3.67 ≤ VAS ≤ 4). Three patients relapsed on one side (one on LFQS, two on HFQS) and five on both sides. Adverse effects included temporary hypopigmentation, hyperpigmentation, uneven pigmentation, and mottled hypopigmentation. Doctors thought 80% of patients were suitable for LFQS. 70% of patients preferred LFQS posttreatment. Conclusions The efficacy difference between the LFQS 1064‐nm laser and HFQS 755‐nm laser in treating CALMs in a 3‐month comparative trial was statistically insignificant. LFQS is preferred by doctors and patients and is likely to help more patients achieve treatment efficacy than the HFQS within a short time, with fewer temporary adverse reactions, and a more even pigmentation. But it can cause mottled hypopigmentation. The LFQS had obvious lesion clearance after the fourth treatment.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Comparison of the safety and efficacy of low fluence Q‐switched 1064‐nm and conventional Q‐Switched 755‐nm lasers in the treatment of café‐au‐lait macules: A prospective self‐controlled trial

et al. 2022

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Treatment of café-au-lait macules with a high-fluenced 1064-nm Q-switched neodymium:yttrium aluminum garnet laser

Kim

Hur²,

Kim³

et al. 2017

Journal of Cosmetic and Laser Therapy

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Café-au-lait macules (CALMs) are light to dark brown macules or patches of increased melanin concentration found along the dermoepidermal junction. Although many attempts to treat CALMs using various kinds of laser/light-based devices have been reported, CALMs remain refractory thereto with high recurrence rates. In this case series, we describe four patients with idiopathic CALMs that were effectively and safely treated with a non-ablative, high-fluenced, Q-switched (QS), 1064-nm neodymium:yttrium aluminum garnet (Nd:YAG) laser. The typical laser parameters for treating CALMs, including a spot size of 7-7.5 mm, a fluence of 2.4-2.5 J/cm, and one to two passes until the appearance of mild erythema, but not petechiae, were utilized in this study over 12-24 treatment sessions at 2-week intervals. We suggest that high-fluenced QS 1064-nm Nd:YAG laser treatment can be used as an effective and alternative treatment modality for CALMs with minimal risk of side effects.

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High‐fluence 1064‐nm Q‐Switched Nd:YAG laser: Safe and effective treatment of café‐au‐lait macules in Asian patients

Baek

Park²,

Lee³

et al. 2018

J of Cosmetic Dermatology

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Combination Treatments of 755 nm Alexandrite Laser with 1,064 nm Nd:YAG Laser Toning for Café Au Lait Macule

Cited by 3 publications

References 7 publications

Comparison of the safety and efficacy of low fluence Q‐switched 1064‐nm and conventional Q‐Switched 755‐nm lasers in the treatment of café‐au‐lait macules: A prospective self‐controlled trial

Comparison of the safety and efficacy of low fluence Q‐switched 1064‐nm and conventional Q‐Switched 755‐nm lasers in the treatment of café‐au‐lait macules: A prospective self‐controlled trial

Treatment of café-au-lait macules with a high-fluenced 1064-nm Q-switched neodymium:yttrium aluminum garnet laser

High‐fluence 1064‐nm Q‐Switched Nd:YAG laser: Safe and effective treatment of café‐au‐lait macules in Asian patients

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