We consider smooth, complex quasi-projective varieties U which admit a compactification with a boundary which is an arrangement of smooth algebraic hypersurfaces. If the hypersurfaces intersect locally like hyperplanes, and the relative interiors of the hypersurfaces are Stein manifolds, we prove that the cohomology of certain local systems on U vanishes. As an application, we show that complements of linear, toric, and elliptic arrangements are both duality and abelian duality spaces.