Combined Effects of Elevated Temperature and Crude Oil Pollution on Oxidative Stress and Apoptosis in Sea Cucumber (Apostichopus japonicus, Selenka)

Li, Xishan; Wang, Chengyan; Li, Nan; Gao, Yali; Ju, Zhonglei; Liao, Guoxiang; Xiong, Dangsheng

doi:10.3390/ijerph18020801

Cited by 23 publications

(6 citation statements)

References 77 publications

(116 reference statements)

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“…The applicability of the time series prediction model is also widely used in river trend, transportation, population migration, urban power consumption, consumption level, etc. [21]. In the economic field, researchers use time series models to judge the trend of capital curve and amount index and use the characteristics of these data to determine the next investment direction of enterprises [22].…”

Section: Application Status Of Time Series Prediction Model In Variou...mentioning

confidence: 99%

The Effect of Temperature on Intestinal Flora Imbalance Based on Time Series Prediction Model

Zhu

Xue

Yang

2022

Journal of Function Spaces

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A series of effects caused by temperature change are the biggest problems faced by biological systems. These irregular environmental characteristics have brought new challenges to people and even animal groups. The immune function of human intestinal flora has a great protective effect on other organs and the body environment. It can help the human body carry out intestinal digestion, food absorption, nutritional metabolism, and so on. Based on the above situation, this paper uses the time series prediction model to study the factors affecting the imbalance of intestinal flora in the process of temperature change. Firstly, biological experiments are carried out with animals to simulate the human environment. Based on the sequence information of historical temperature change parameters, a temperature prediction device based on time series model is proposed. The effects of air factors and carbon dioxide content on the prediction results are evaluated by statistical analysis. Secondly, in order to ensure the accuracy of the experimental data, the neural network algorithm is used to optimize the model, and the white blood cell count is used to analyze the influence of temperature change on the intestinal flora structure of the two organisms. Finally, the experimental results are applied to the human environment to analyze the research results. The results showed that with the irregular change of temperature, the number of intestinal flora and internal colony structure also changed. The richness index in the normal temperature environment is relatively large, which can effectively explain the high richness of intestinal microflora in the experimental population. Further analyze the subjects and distinguish the animals according to sex. The number of Bacteroides in the intestinal flora of male animals was higher than that of female animals, but this phenomenon disappeared immediately after physical ligation. In addition, the intestinal flora abundance of female animals is higher than that of male animals, and the metabolic level is faster.

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Section: Application Status Of Time Series Prediction Model In Variou...mentioning

confidence: 99%

The Effect of Temperature on Intestinal Flora Imbalance Based on Time Series Prediction Model

Zhu

Xue

Yang

2022

Journal of Function Spaces

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“…Recent studies have revealed that increased summer temperatures have a stronger impact on Solea fish due to increased physiological activity and metal uptake than lower winter temperatures [27,28]. Biomarker responses demonstrate similar patterns in several fish species, as evidenced by the elevated oxidative stress [29][30][31], genotoxicity [32][33][34], and stress proteins [35][36][37]. There is a paucity of information with respect to Solea aegyptiaca inhabiting Lake Qarun, as well as the effect of seasonal variations on these biomarkers.…”

Section: Introductionmentioning

confidence: 99%

Integrated use of biomarkers to assess the impact of heavy metal pollution on Solea aegyptiaca fish in Lake Qarun

et al. 2022

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Background Biomarkers have become a valuable tool in environmental assessment, since they contribute to predicting contaminants in monitoring programmes. This study aimed to investigate the toxicity of heavy metal pollution in Lake Qarun using a multibiomarker approach (morphological, oxidative stress, genotoxicity, stress proteins) in Solea aegyptiaca fish. During the winter and summer seasons, water and fish samples were collected from different locations along Lake Qarun; western and northern sectors were away from any source of pollution, while southern and eastern sectors were exposed to effluents discharged from El-Wadi and El-Bats drains, respectively. The environmental quality, as well as the accumulation of metals (Fe, Cu, Zn, Cd, Pb, Ni) in fish gills, liver, and muscles were assessed. Data were integrated using the integrated biomarker response index (IBRv2) for biomarker response interpretation. Results Water quality and bioaccumulation of heavy metals revealed a highly significant difference between samples collected from polluted sectors and those collected far from drainage water, and, seasonal differences were detected. Growth indices revealed a significant difference between sites and seasons. Fish from the western sector had the highest total antioxidant capacity in their gills, liver, and muscles, with no seasonal differences detected. However, the maximum value of malondialdehyde, protein carbonyl, 8-hydroxy-2′deoxyguanosine, metallothionein, heat shock protein 70, and DNA strand breaks in gills, liver, and muscles was detected in the polluting sectors. It revealed a significant difference between seasons, with the highest value during the winter season. According to IBRv2 results, the most effective biomarkers in this study were malondialdehyde and 8-hydroxy-2′deoxyguanosine in gills, protein carbonyl and metallothionein in the liver, heat shock protein 70 in gills and liver, and DNA strand break in gills, liver, and muscles. Conclusions This multibiomarker approach contributes to distinguishing between locations with varying levels of anthropogenic pollution, identifying the drainage water-exposed sectors as the most stressed and the winter season as the most critical time for Solea aegyptiaca owing to spawning. The biomarkers chosen are effective indicators in Solea aegyptiaca under stress, indicating the potential for environmental monitoring. Graphical Abstract

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“…In the present study, changes in antioxidant enzymes in the most polluted areas were sufficient to prevent increases in MDA levels. However, previous studies have observed an increase in ROS levels and oxidative damage markers in A. japonicus exposed to MPs, benzo[a]pyrene (BaP), or crude oil under controlled conditions [ 71 , 74 , 75 ]. Similarly, no significant changes in AChE activity were observed between the areas studied, indicating the absence of neurotoxicity.…”

Section: Discussionmentioning

confidence: 99%

Effects of Human Activity on Markers of Oxidative Stress in the Intestine of Holothuria tubulosa, with Special Reference to the Presence of Microplastics

Lombardo

Solomando

Cohen-Sánchez

et al. 2022

IJMS

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Pollution in the seas and oceans is a global problem, which highlights emerging pollutants and plastics, specifically microplastics (MPs), which are tiny (1 μm to 5 mm) ubiquitous plastic particles present in marine environments that can be ingested by a wide range of organisms. Holothurians are benthic organisms that feed on sediment; therefore, they can be exposed to contaminants present in the particles they ingest. The objective was to evaluate the effects of human activity on Holothuria tubulosa through the study of biomarkers. Specimens were collected in three different areas throughout the island of Eivissa, Spain: (1) a highly urbanized area, with tourist uses and a marina; (2) an urbanized area close to the mouth of a torrent; (3) an area devoid of human activity and considered clean. The results showed a higher presence of microplastics (MPs) in the sediments from the highly urbanized area in relation to the other two areas studied. Similarly, a higher number of MPs were observed in the digestive tract of H. tubulosa from the most affected area, decreasing with the degree of anthropic influence. Both in the sediment and in the holothurians, fibers predominated with more than 75% of the items. In the three areas, mesoplastics were analyzed by means of FTIR, showing that the main polymer was polypropylene (27%) followed by low-density polyethylene (17%) and polystyrene (16%). Regarding the biomarkers of oxidative stress, the intestine of H. tubulosa from the most impacted areas showed higher catalase, superoxide dismutase (SOD), glutathione reductase (GRd), and glutathione S-transferase (GST) activities and reduced glutathione (GSH) levels compared to the control area. The intermediate area only presented significant differences in GRd and GST with respect to the clean area. The activities of acetylcholinesterase and the levels and malondialdehyde presented similar values in all areas. In conclusion, human activity evaluated with the presence of MPs induced an antioxidant response in H. tubulosa, although without evidence of oxidative damage or neurotoxicity. H. tubulosa, due to its benthic animal characteristics and easy handling, can be a useful species for monitoring purposes.

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Combined Effects of Elevated Temperature and Crude Oil Pollution on Oxidative Stress and Apoptosis in Sea Cucumber (Apostichopus japonicus, Selenka)

Cited by 23 publications

References 77 publications

The Effect of Temperature on Intestinal Flora Imbalance Based on Time Series Prediction Model

The Effect of Temperature on Intestinal Flora Imbalance Based on Time Series Prediction Model

Integrated use of biomarkers to assess the impact of heavy metal pollution on Solea aegyptiaca fish in Lake Qarun

Effects of Human Activity on Markers of Oxidative Stress in the Intestine of Holothuria tubulosa, with Special Reference to the Presence of Microplastics

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